“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas

The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.

The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.

skin cancer
Skin Sheltered from Sunlight Still Gathers UV-Linked Mutations
Skin Sheltered from Sunlight Still Gathers UV-Linked Mutations
Abby Olena | Jan 14, 2021
Whole-genome sequencing reveals a wide range of UV-induced DNA changes in human skin cells, and lighter skin collects more mutations, sometimes to “sky high” levels.
Sunscreen Ingredients Absorbed into Blood: Study
Sunscreen Ingredients Absorbed into Blood: Study
Catherine Offord | May 7, 2019
FDA researchers report that multiple active ingredients wind up in users’ bloodstream and recommend toxicology testing to investigate the clinical significance of the findings.
Cancer Vaxxer: A Profile of Miriam Merad
Cancer Vaxxer: A Profile of Miriam Merad
Anna Azvolinsky | Apr 1, 2019
The Mount Sinai oncologist studies innate immune cells with the goal of designing novel immunotherapies, including cancer vaccines.
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Ashley Yeager | Mar 21, 2019
Certain populations have been historically underrepresented in genome sequencing studies, but the NIH, private clinics, and 23andMe and other companies are trying to fix that.
Taller People More Prone to Cancer
Taller People More Prone to Cancer
Abby Olena | Oct 24, 2018
The increased risk is slight, but aligns with a longstanding hypothesis that having more cells in one’s body leads to more chances for those cells to become cancerous.
Cancer-Fighting Chemical Found in Human Skin Bacteria
Cancer-Fighting Chemical Found in Human Skin Bacteria
Diana Kwon | Mar 1, 2018
A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.
Image of the Day: Sun Burn
Image of the Day: Sun Burn
The Scientist Staff, The Scientist Staff | Oct 20, 2017
When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.
Image of the Day: Manipulative Melanomas
Image of the Day: Manipulative Melanomas
The Scientist Staff | Mar 19, 2017
Early-stage melanoma cells alter proteins in nearby skin cells to create a favorable environment for cancer progression.
“Redhead” Gene Variant Boosts Melanoma Risk
“Redhead” Gene Variant Boosts Melanoma Risk
Tanya Lewis | Jul 12, 2016
People without red hair who possess the variant are also more likely to develop this form of skin cancer, researchers report.
Fuchs on the Future
Fuchs on the Future
The Scientist Staff | Apr 30, 2016
Rockefeller University researcher Elaine Fuchs on being a woman in science and her contributions to the burgeoning field of reverse genetics
Antioxidants Facilitate Melanoma Metastasis
Antioxidants Facilitate Melanoma Metastasis
Anna Azvolinsky | Oct 7, 2015
Two compounds boost the ability of melanoma cells to invade other tissues in mice, providing additional evidence that antioxidants can be beneficial to malignant cells as well as healthy ones.
Cancer-Driving Mutations Common in Normal Skin Cells
Cancer-Driving Mutations Common in Normal Skin Cells
Anna Azvolinsky | May 21, 2015
A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 
The Dark Side of Melanin
The Dark Side of Melanin
Anna Azvolinsky | Feb 19, 2015
Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.
Testicular-Skin Cancer Tradeoff
Testicular-Skin Cancer Tradeoff
Bob Grant | Oct 14, 2013
A genetic mutation tied to risk of developing testicular cancer may be more prevalent in white men because it also confers a reduced risk of developing skin cancer.
Blue Whales Get Tans
Blue Whales Get Tans
Kate Yandell | Sep 2, 2013
The large mammals alter the levels of melanin in their skin depending on sun exposure, helping them to avoid DNA damage.
Master of Fate
Master of Fate
Megan Scudellari | Jul 1, 2013
While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.
 
Odor-like Biomarkers for Skin Cancer
Odor-like Biomarkers for Skin Cancer
Dan Cossins | Jun 17, 2013
Researchers identify a unique chemical signature associated with human melanoma cells that could lead to new ways to screen for the disease.
 
An Epi Phenomenon
An Epi Phenomenon
Karen Hopkin | Dec 1, 2012
While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.
Gingers More Prone to Skin Cancer
Gingers More Prone to Skin Cancer
Jef Akst | Nov 1, 2012
Researchers identify an unexpected molecular explanation for the higher incidence of skin cancer in redheads.