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Artist’s rendition of the molecular structure of a ribosome (blue and purple) as it produces a polypeptide chain (red) from an mRNA template (orange and gray), with tRNA molecules (dark purple) shuttling amino acids.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

spermatogenesis

Human Testicles Contain Endocannabinoid System Components
Ruth Williams | Sep 19, 2019 | 3 min read
Proteins that synthesize, bind, and degrade endocannabinoids are present in the body’s sperm factories, suggesting that the use of cannabis may directly affect them.
Image of the Day: Sperm Protectors
The Scientist | Aug 18, 2017 | 1 min read
Among their many functions, macrophages in mouse testes guard sperm against attacks by other immune cells. 
Week in Review: February 22–26
Jef Akst | Feb 26, 2016 | 3 min read
Questions about how E. coli evolves; spermatids in a dish; fighting bacteria with virus-like molecule; what drives metastasis; antibodies fight Ebola in monkeys
Toward Making Sperm in the Lab
Rina Shaikh-Lesko | Feb 25, 2016 | 3 min read
Researchers devise a technique for creating gametes from murine embryonic stem cells.
Surrogate Genes Enable Reproduction
Jyoti Madhusoodanan | Jan 28, 2016 | 3 min read
Increasing the expression of two genes from non-Y chromosomes restores spermatogenesis in male mice that lack Y chromosomes.
Sperm From Ovaries
Anna Azvolinsky | Jun 11, 2015 | 3 min read
With the deletion of a single gene, female Japanese rice fish can produce sperm. 
Sperm Stem Cell Maintenance
Jenny Rood | Mar 2, 2015 | 1 min read
A missing transcription factor puts an early end to sperm production in mice.
Fat Dads’ Epigenetic Legacy
Kate Yandell | Feb 7, 2013 | 3 min read
Children with obese fathers show epigenetic changes that may affect their health.
Creating Sperm from Skin
Hayley Dunning | Aug 30, 2012 | 1 min read
Researchers create early stage sperm cells from induced pluripotent stem cells, raising hopes that infertile men could be fathers.
Hope for Male Contraception
Sabrina Richards | Aug 16, 2012 | 4 min read
A small molecule that inhibits a protein important for chromatin organization can cause reversible sterility in male mice.
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