Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons
So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.
Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

synapse
Hippocampal Cell Communication Is Bidirectional: Study
Hippocampal Cell Communication Is Bidirectional: Study
Christie Wilcox | Jun 4, 2021
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
Abby Olena | May 20, 2021
The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.
Can Single Cells Learn?
Can Single Cells Learn?
Catherine Offord | May 1, 2021
A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.
Flexible Synapse Strength May Underpin Mammal Brain’s Complexity
Flexible Synapse Strength May Underpin Mammal Brain’s Complexity
Asher Jones | Mar 24, 2021
Neural connections in the mouse neocortex can release multiple packages of neurotransmitters per electrical impulse, a study finds.
Infographic: A New Model of Synapse Strength
Infographic: A New Model of Synapse Strength
Asher Jones | Mar 24, 2021
Synapses in the mouse neocortex can release multiple packages of neurotransmitters, suggesting that connection strength is more flexible than previously thought.
How Immune Cells Make the Brain Forget
How Immune Cells Make the Brain Forget
Ashley Yeager | May 1, 2020
Microglia ingest nerve cell connections, leading to the loss of information stored in neuronal circuits.
Aggressive Cancers Feed Off the Brain’s Nerves
Aggressive Cancers Feed Off the Brain’s Nerves
Emily Makowski | Sep 20, 2019
Three studies show that tumor cells can behave like neurons.
New Technique Captures Entire Fly Brain in 3D
New Technique Captures Entire Fly Brain in 3D
Carolyn Wilke | Jan 18, 2019
The method combines two approaches to reveal a high-resolution map of all 40 million synapses.
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice
Diana Kwon | Sep 10, 2018
The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.
Artificial Nerve Senses Pressure, Moves Cockroach Leg
Artificial Nerve Senses Pressure, Moves Cockroach Leg
Shawna Williams | May 31, 2018
The device could one day help enable prosthetics deliver richer touch information to users.
RNA Moves a Memory From One Snail to Another
RNA Moves a Memory From One Snail to Another
Ashley Yeager | May 14, 2018
Injecting molecules from a sea slug that received tail shocks into one that didn’t made the recipient animal behave more cautiously. 
Certain Glial Cells Appear to Help Prevent Muscle Fatigue
Certain Glial Cells Appear to Help Prevent Muscle Fatigue
Ashley Yeager | May 1, 2018
The flow of calcium and potassium ions keeps muscles contracting in the diaphragms of neonatal mice, but if a key protein receptor is missing, fatigue sets in more quickly.
Infographic: Getting Synapses Ready to Fire
Infographic: Getting Synapses Ready to Fire
Ashley Yeager | Apr 30, 2018
A new study reveals more about the role of specialized Schwann cells at junctions between neurons and muscle cells.
Neurons Use Virus-Like Proteins to Transmit Information
Neurons Use Virus-Like Proteins to Transmit Information
Diana Kwon | Jan 15, 2018
In mice and flies, the Arc protein forms capsids and carries genetic information.
First In Vivo Function Found for Animal Circular RNA
First In Vivo Function Found for Animal Circular RNA
Catherine Offord | Aug 10, 2017
Mice lacking the RNA had deregulated microRNAs in the brain, disrupted synaptic communication, and behavioral abnormalities associated with neuropsychiatric disorders.
Memories Erased from Snail Neurons
Memories Erased from Snail Neurons
Diana Kwon | Jun 28, 2017
Scientists block particular enzymes to remove the cellular signatures associated with specific memory types.  
Neuron Signaling Persists, Faintly, Even When Key Presynaptic Proteins Are Absent
Neuron Signaling Persists, Faintly, Even When Key Presynaptic Proteins Are Absent
Ben Andrew Henry | Nov 1, 2016
Results from experiments in mice revise a long-held hypothesis that certain protein scaffolds are needed for synaptic activity.
Two-Photon Microscopy’s Historic Influence on Neuroscience
Two-Photon Microscopy’s Historic Influence on Neuroscience
Alison F. Takemura | Nov 1, 2016
In the 1990s, the development of this gentler and more precise microscopy method improved scientists’ ability to probe neurons’ activity and anatomy.
Brain Prize Winners Announced
Brain Prize Winners Announced
Catherine Offord | Mar 3, 2016
Three UK neuroscientists jointly win the €1 million European Brain Prize for their work on memory.