High salt concentrations are present in the affected skin of people with atopic dermatitis and promote the differentiation of the T helper cells involved in the development of allergic diseases.

By uncovering novel properties of a unique population of T cells, the Scripps Research Institute immunologist has helped to redefine the immune cells, uncovering their role in wound healing.

The immunologists, honored with the 2018 award in Physiology or Medicine, pioneered immunotherapy, which harnesses the body’s immune system to fight cancer.

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.

Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.  

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections.