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New Insights to Improve CAR T Cells’ Safety
Vicki Brower | Jun 5, 2018
Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Genetic Screen Predicts T-Cell Lymphoma Aggression
Kerry Grens | May 9, 2018
Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Antiviral Immunotherapy Comes of Age
Lucas Laursen | Dec 4, 2017
T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections.
Researchers Build a Cancer Immunotherapy Without Immune Cells
Abby Olena | Nov 13, 2017
A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro.
FDA Approves Second CAR T-Cell Therapy
Ashley P. Taylor | Oct 19, 2017
The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas.
Compound Found in Red Wine Boosts Immune Cell Function
Catherine Offord | Oct 16, 2017
At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling.
The Ever-Expanding T-Cell World: A Primer
Ashley P. Taylor | Aug 7, 2017
Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer.
attempts to catalog them all.