CRISPR, TALENs, ZFNs, gene editing, base editing, mitochondria, DNA, mtDNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA

An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.

An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.

TALENs
Infographic: A Gene Editor for Plant Mitochondrial DNA
Ruth Williams | Mar 1, 2020
New TALEN-based tools enable the organelle’s genome to be targeted and modified.
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
buri recombinetics hornell cow hereford bull polled genetically engineered talens gmo cattle livestock
Genome-Edited Hornless Cows’ Offspring Are Healthy: Study
Kerry Grens | Oct 9, 2019
All six calves inherited the gene for preventing horn growth, but four also got a piece of the plasmid used to introduce the sequence to their dad—complicating regulatory approval.
Gene-Edited Soybean Oil Makes Restaurant Debut
Carolyn Wilke | Mar 13, 2019
A Minnesota-based company reports the sale of a soybean oil engineered to have greater stability and no trans-fat.
Gene Editing Treats Mitochondrial Disorders in Mice
Catherine Offord | Sep 25, 2018
Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.
Thirty Years of Progress
The Scientist Staff | Oct 1, 2016
Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.
Gene Editing: From Roots to Riches
Amanda B. Keener | Oct 1, 2016
Advances in genetic manipulation have simplified the once daunting task of rewriting a gene.
Treating Cancer with CRISPR?
Jef Akst | Jun 17, 2016
A federal panel will review the first proposal for the use of the technology to edit human genes for medical purposes.
Genetically Engineered Hornless Dairy Calves
Jef Akst | May 10, 2016
Researchers use a gene editor to introduce an allele that eliminates the horned trait—and thus, the need for an expensive and painful process of dehorning—in dairy cows.
Gene Editing Treats Leukemia
Karen Zusi | Nov 6, 2015
One-year-old Layla Richards has remained cancer-free months after receiving an experimental gene editing therapy.
Gene-Edited Pets
Karen Zusi | Oct 2, 2015
Genomics giant BGI announces plans to sell “micro-pigs” it originally developed for research.
New Way to Edit Genes
Jef Akst | Oct 1, 2015
Researchers develop a more-efficient method for rewriting DNA that could hold therapeutic value for HIV and other diseases.
Erasing Mitochondrial Mutations
Jenny Rood | Apr 23, 2015
Researchers develop a method to selectively remove mutated mitochondrial DNA from the murine germline and single-celled mouse embryos.
Engineering TB-Resistant Cows
Jenny Rood | Mar 3, 2015
Scientists add a mouse gene to the cow genome to ward off bovine tuberculosis.
A CRISPR Fore-Cas-t
Carina Storrs | Mar 1, 2014
A newcomer’s guide to the hottest gene-editing tool on the block