a baby's feet
“Three-Parent” IVF Trialed for Infertility
A company announces the first pregnancy in a study of whether donor mitochondria can boost IVF’s odds of success.
“Three-Parent” IVF Trialed for Infertility
“Three-Parent” IVF Trialed for Infertility

A company announces the first pregnancy in a study of whether donor mitochondria can boost IVF’s odds of success.

A company announces the first pregnancy in a study of whether donor mitochondria can boost IVF’s odds of success.

three-parent IVF
Opinion: Three-Parent Embryos—A Slippery Slope?
John D. Loike, Alan Kadish | Jun 14, 2018
The use of pronuclear transfer to treat infertility must first be backed by evidence it can work in cases where parents seek to avoid mitochondrial mutations.
Details of First Three-Parent IVF Revealed
Bob Grant | Apr 3, 2017
The team that oversaw the first use of mitochondrial replacement therapy that resulted in a live birth has published an account of the procedure.
U.K. Moves Forward With Three-Parent IVF
Bob Grant | Mar 20, 2017
The country’s fertility regulator has approved the first application to carry out mitochondrial replacement therapy, which uses biological material from two women and one man to create an embryo.
Contributors
Ben Andrew Henry | Jan 1, 2017
Meet some of the people featured in the January 2017 issue of The Scientist.
Gene Drives and Other Controversies
Mary Beth Aberlin | Jan 1, 2017
Aedes and Anopheles control; three-parent babies; the PhD glut
Life Science Controversies of 2016
Bob Grant, Jef Akst, Tracy Vence | Dec 23, 2016
This year, the developers of CRISPR gene-editing technology argued over patent rights, a researcher fought to unmask anonymous PubPeer commenters, US regulators considered “three-parent” babies, and troubles continued for Theranos.
Opinion: Ethical Considerations of “Three-Parent” Babies
John D. Loike and Nancy Reame | Dec 22, 2016
Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.
Britain Set to Become First Country to Approve Three-Parent IVF
Joshua A. Krisch | Dec 15, 2016
Parliament voted to allow mitochondrial replacement therapy last year. This latest decision suggests we may see babies born from the technique in the country in 2017.
Three-Parent IVF Advances
Anna Azvolinsky | Nov 30, 2016
Differences in the replicative advantages conferred by some mitochondrial DNA haplotypes have implications for mitochondrial replacement therapy, researchers report. 
TS Picks: October 24, 2016
Tracy Vence | Oct 24, 2016
Theranos’s bad blood tests; presidential science lessons; “three-parent” babies
First MRT Baby Born
Bob Grant | Sep 28, 2016
Scientists in Mexico achieved the infant’s conception using mitochondrial replacement therapy. 
Improving Mitochondrial Replacement Therapy
Anna Azvolinsky | Jun 8, 2016
Pronuclear transfer can reduce the risk of transferring defective mitochondria, a study shows.  
IOM: Mitochondrial Replacement “Ethically Permissible”
Tracy Vence | Feb 4, 2016
Experts from the US National Institute of Medicine outline their conditional approval of clinical research on mitochondrial replacement techniques.
UK OKs Three-Parent IVF
Bob Grant | Feb 25, 2015
The British House of Lords has approved new rules regarding the creation of embryos using genetic material from three donors.
UK Supports Three-Parent IVF
Jef Akst | Feb 3, 2015
Parliament today voted to allow techniques that could help couples produce babies with a reduced chance of passing on heritable mitochondrial diseases.
Three-Parent Babies in “Two Years”
Bob Grant | Jun 5, 2014
The U.K.’s human embryo research agency says that a new mitochondrial replacement technique is safe and could be approved soon, paving the way for three-parent IVF.
UK To Legalize Three-Parent IVF?
Bob Grant | Mar 3, 2014
Regulators in England near the approval of a new mitochondrial replacement technique for creating embryos with less risk of developing certain heritable diseases.