Diffuse star-like shapes with regions in purple, green, and both colors overlapped.
Tumor Cells on Brink of Death May Trigger Metastasis
A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.
ABOVE: ARIEL RUIZ I ALTABA
Tumor Cells on Brink of Death May Trigger Metastasis
Tumor Cells on Brink of Death May Trigger Metastasis

A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.

A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.

ABOVE: ARIEL RUIZ I ALTABA

tumor cells

A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Devin A. Reese | Mar 1, 2022
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
Defined Primary Cell Culture and Media
The Scientist Creative Services Team in collaboration with MilliporeSigma | Jul 29, 2021
A new partnership opens the door for a source of highly purified human primary cells and defined cell culture media.
Scanning electron micrograph showing cancer cell attached to T call via nanotube
Cancer Cell Nanotubes Hijack Mitochondria from Immune Sentinels
Sophie Fessl | Nov 30, 2021
The mitochondria stolen via these tiny connections give tumor cells a metabolic boost while the T cells are left weakened, according to in vitro experiments.
visualization of p53 protein interacting with its inhibitors MDM2 and MDMX
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
Marcus A. Banks | Jul 29, 2021
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
How Cancer Evades the Immune System
The Scientist Creative Services Team | Aug 31, 2020
Presenters in this webinar will discuss how cancer not only evades the immune system, but also co-opts it to promote tumor growth.
Infographic: Steps in Cancer Metastasis
Shawna Williams | Apr 1, 2021
It’s now thought that in many cases, cancer cells disseminate from the primary tumor site early on and lie dormant for long periods rather than only venturing out from primary tumors at an advanced stage.
Bispecific Antibodies Treat Cancer in Mouse Models
Abby Olena | Mar 5, 2021
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
CAR T cells, oncolytic virus, CD19, mouse model, solid cancer, liquid cancer, tumor, immune response, immunotherapy, T cell, treatment
Immunotherapy Combo Reduces Solid Tumors in Mice
Amanda Heidt | Sep 9, 2020
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.
Colon Cancer Uses a Regenerative Playbook to Metastasize
Shawna Williams | Apr 1, 2020
A study finds similarities between cells that heal wounds and those that lead deadly cancerous invasions.
Cancer-Fighting Chemical Found in Human Skin Bacteria
Diana Kwon | Mar 1, 2018
A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.
How Cancers Evolve Drug Resistance
Anna Azvolinsky | Apr 1, 2017
Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.
Infographic: Mechanisms of Resistance
Anna Azvolinsky | Mar 31, 2017
Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Lipids Take the Lead in Metastasis
Amanda B. Keener | Jan 20, 2017
Researchers find diverse ways that the molecules can regulate cancer’s spread.
Circulating Tumor Cells Traverse Tiny Vasculature
Tanya Lewis | Apr 18, 2016
Clusters of tumor-derived cells can pass through narrow channels that mimic human capillaries, scientists show in vitro and in zebrafish.
Dying Light Marks the Spot
Catherine Offord | Mar 28, 2016
Drug-delivering nanoparticles designed to glow when their target cells die can report on the effectiveness of cancer therapies within just a few hours of treatment, a mouse study shows.
An Epi Phenomenon
Karen Hopkin | Dec 1, 2012
While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.