tumor suppression

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

The same microRNAs can have opposing roles in cancer.

Even when a clinical trial fails, some patients improve. What can researchers learn from these exceptional responders?

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

A panel of oncologists discusses cases of exceptional responders, or cancer patients whose tumors disappear after a brief period of chemotherapy.

Advances in genomics and cancer biology will alter the design of human cancer studies.

Researchers have pinpointed the region of a key cancer gene that’s involved in tumor suppression.