This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.

Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.

The move, which is not supported by the pharmaceutical industry, would allow other countries to design and manufacture COVID-19 vaccines without fear of litigation.

Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.

Following vaccination, some women claim their periods have changed, leading to rumors about how the shots affect recipients’ reproductive systems, and even others’ by proxy.  

Stanford University researchers determined the code from spare drops in discarded vials of the COVID-19 vaccine and published it on GitHub.

Vaccines against various forms of cancer prime the immune system to attack.

Preliminary results from an Israel-based study suggest that one dose of the vaccine reduces infectiousness—a key factor in slowing virus spread.

An expert panel will present how synthetic biology accelerates the development of diagnostics, therapeutics, and the medicinal pipeline.

A preprint casts doubt on vaccine effectiveness in light of certain mutations in the 501Y.V2 variant that emerged from South Africa.

From new treatments to an investigation into the virus’s origins, here are some of the developments we can expect this year.

The majority of people experiencing anaphylaxis had a history of allergic reactions, a report by the agency finds.

The world was rocked by the COVID-19 pandemic this year, but researchers rose to all manner of challenges.

Researchers turn to familiar model animals, along with some fresh strategies, to develop countermeasures against SARS-CoV-2 and investigate the biology of infection.

Meet some of the people featured in the November 2020 issue of The Scientist.

A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.

Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.

In the past, it was not uncommon for researcher to test their experimental therapeutics and vaccines on themselves. Some even volunteered to be exposed to pathogen-carrying vectors.

Repurposing Living Systems to Fight a Pandemic