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Accumulating lipids may be Wolbachia bacteria’s secret weapon for decreasing viral transmission.

viral replication

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Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

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Scanning Viral Genomes with 300mer Oligonucleotides

Insects Pass Antiviral Immunity to Offspring

Gene Splicing Pioneer Dale Kaiser Dies

Why Some COVID-19 Cases Are Worse than Others

Some Viruses May Infect by Inserting Different Portions of Genetic Material

Researchers Develop a Drug Against the Common Cold

Maternal Response to Zika Damages Mouse Fetuses

Ebola RNA Found Hiding in Health-Care Worker’s Lungs

CRISPR Combats Herpes

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Hidden Menace

Hide and Seek

Where Rhinovirus Replicates Best

Nipah Protein Structure Revealed

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Sex Determination: It’s in the Genes—Sometimes

A group of large animals, some of which are being studied for cancer resistance genes and proteins, are pictured, including a bison, an elephant, a giraffe, a manatee, a zebra, and a whale.

Peto’s Paradox: How Gigantic Species Evolved to Beat Cancer

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An artistic rendition of polycystic ovarian syndrome, showing ovarian cysts represented by paper balls.

An Anti-Malarial Drug Could Ameliorate PCOS Symptoms

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Olink® Reveal: Accessible NGS-based proteomics for every lab

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Discover the history, mechanics, and potential of PCR.

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March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

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Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

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3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

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Navigating Cold Storage Solutions

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The Immunology of the Brain

The Immunology of the Brain

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New DeNovix Helium Nano Volume Spectrophotometer

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Olink® Reveal: Accessible NGS-based proteomics for every lab

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Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit