viral replication

A new genetic sensor called PRISM makes use of a host cell’s DNA replication machinery to trigger fluorescence in neurons with damaged DNA.

A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.

Researchers use long custom oligos to screen viral genome stability with an NGS workflow.

In both Drosophila and mosquitoes, protection lasts for generations following a single maternal exposure to positive-sense single-stranded RNA viruses.

Working with a virus that infects bacteria, the Stanford University biochemist and developmental biologist helped to develop a way to stitch DNA together, a discovery that gave rise to genetic engineering.

Emerging data as well as knowledge from the SARS and MERS coronavirus outbreaks yield some clues as to why SARS-CoV-2 affects some people worse than others.

Viruses that infect plants and occasionally insects appear to cause infection with a divide-and-conquer strategy, multiplying separate segments of genetic material in different host cells.

In an in vitro study, the compound completely blocked the replication of rhinoviruses.

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

A case study reports evidence of viral replication lingering in the respiratory tract of an infected person, even after the person’s blood was Ebola free.

Scientists use the gene editing technology to target active and latent virus in mammalian cell cultures.

A guide to culturing cells with viruses in mind

Curing HIV means finding and eradicating viruses still lurking in the shadows.

Oxford researcher John Frater explains the strategy of targeting viral reservoirs to beat HIV.

A mouse study shows that the common cold-causing virus replicates better in the cooler nasal cavity than in the warmer lung.

The structure of a key protein of the deadly virus could serve as a stepping stone to antiviral therapy.