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Accumulating lipids may be Wolbachia bacteria’s secret weapon for decreasing viral transmission.

viral replication

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Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

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Scanning Viral Genomes with 300mer Oligonucleotides

Insects Pass Antiviral Immunity to Offspring

Gene Splicing Pioneer Dale Kaiser Dies

Why Some COVID-19 Cases Are Worse than Others

Some Viruses May Infect by Inserting Different Portions of Genetic Material

Researchers Develop a Drug Against the Common Cold

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Universe 25 Experiment

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Why Do Dogs Love Peanut Butter?

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Criticism of Autism-Gut Microbiome Research Sparks Pushback

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Exploring the Vast Potential of Oxford Nanopore Sequencing for Clinical Research

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Driving Innovation with Cell Culture Essentials

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Driving Innovation with Cell Culture Essentials

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December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
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Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

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Exploring the Inflammatory Tumor Microenvironment 

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A Comprehensive Guide to Next-Generation Sequencing

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

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Enter Our 2026 Top Innovations Contest

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Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS