Insects Pass Antiviral Immunity to Offspring

In both Drosophila and mosquitoes, protection lasts for generations following a single maternal exposure to positive-sense single-stranded RNA viruses.

Written byAbby Olena, PhD
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Insects don’t make the cells and antibodies characteristic of the vertebrate adaptive immune response. As a result, scientists assumed for years that insects rely on innate immune defenses that are neither heritable nor directed at any pathogen in particular. Over the last 20 years, though, evidence has emerged that invertebrates do inherit some types of immunity from their parents, but it’s still not clear how or how often it happens. In a study published December 15 in Cell Reports, researchers show that fruit flies (Drosophila melanogaster) and mosquitoes (Aedes aegypti) pass immunity to viruses to their progeny for multiple generations.

“The authors present a very thorough set of experiments that detail the existence of this transfer of some kind of immunological memory to the offspring from generation to generation,” says Barbara Milutinović, a postdoc at the Institute of Science and Technology Austria who did not participate ...

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  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

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