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Explore a comprehensive guide to standardizing large scale production and clarification of lentiviral vectors.

viral vectors

An illustration of orange, blue, and grey lentiviral particles on a white background.

Scaling Up Lentiviral Vector Manufacturing 

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An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

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Conceptual vector image of scientist engage in molecular biology research.

Helper Plasmids Lend a Hand to AAV Production

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Discover What Digital PCR Can Do Across a Wide Range of Applications

Digital PCR Applications

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Equally-sized droplets of a nucleic acid sample.

Digital PCR: The Journey to Superior Data 

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Defending against Dravet

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The Heart Can Directly Influence Our Emotions

Learn How Researchers Make the Most of Viral Vectors for Gene Therapy

Viral Vector Platforms for Gene Therapy

How to Produce Successful Viral Vectors 

How to Produce Successful Viral Vectors

Learn how researchers develop novel vaccines with new technologies 

The Vaccine Journey: From Bench to Needle

Learn about establishing a Gene Therapy Manufacturing Strategy 

Considerations for Gene Therapy Manufacturing Strategies

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

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Shining a Light on Mass Photometry

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Colin Carlson Works to Predict and Prevent Viral Spillover

Sleeping mice in chambers with mosquitoes behind them on a mesh

Mosquitoes Drawn to Hosts Infected by Dengue, Zika

Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.

Extracellular Vesicles: Applications and Potential

Explore Solutions for Cell and Gene Therapy Development

Cell and Gene Therapy from the Bench to the Clinic

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New Preprints Further Implicate Market in Pandemic’s Origins

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Capturing Heterogeneity: How Single Cell Analysis Reshapes Health and Disease Research

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Immune Amnesia: How the Texas Measles Outbreak Could Promote the Spread of Other Infectious Diseases

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Universe 25 Experiment

An infant thinking and possibly forming memories.

Babies Form Memories. Why Do Adults Forget Them?   

3D illustration of a blue virus (center) surrounded by magenta antibodies. More blue viruses are in the background.

Viruses That Mimic Human Proteins May Be More Common than Previously Thought  

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The Advent of Automated and AI-Driven Benchwork

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Olink® Reveal: Accessible NGS-based proteomics for every lab

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March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
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The Advent of Automated and AI-Driven Benchwork

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Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

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Genetic Insights Break Infectious Pathogen Barriers

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A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

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Products

Sapio Sciences

Sapio Sciences Makes AI-Native Drug Discovery Seamless with NVIDIA BioNeMo

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New DeNovix Helium Nano Volume Spectrophotometer

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Olink® Reveal: Accessible NGS-based proteomics for every lab

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Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit