A circular yellow T cell with yellow and blue receptors.
| 3 min read
A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

viral vectors

A man in a blue shirt holds a pinkish paper cut out of a pair of lungs.

Genetic Engineering Hides Donor Organs from Host Immune System

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Scaling Up Lentiviral Vector Manufacturing 

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An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

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Helper Plasmids Lend a Hand to AAV Production

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Discover What Digital PCR Can Do Across a Wide Range of Applications

Digital PCR Applications

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Digital PCR: The Journey to Superior Data 

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Defending against Dravet

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The Heart Can Directly Influence Our Emotions

Learn How Researchers Make the Most of Viral Vectors for Gene Therapy

Viral Vector Platforms for Gene Therapy

How to Produce Successful Viral Vectors 

How to Produce Successful Viral Vectors

Learn how researchers develop novel vaccines with new technologies 

The Vaccine Journey: From Bench to Needle

Learn about establishing a Gene Therapy Manufacturing Strategy 

Considerations for Gene Therapy Manufacturing Strategies

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

An immunoglobulin, also known as an antibody, floating in solution.

Shining a Light on Mass Photometry

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Colin Carlson Works to Predict and Prevent Viral Spillover

Sleeping mice in chambers with mosquitoes behind them on a mesh

Mosquitoes Drawn to Hosts Infected by Dengue, Zika

Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.

Extracellular Vesicles: Applications and Potential

Explore Solutions for Cell and Gene Therapy Development

Cell and Gene Therapy from the Bench to the Clinic

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New Preprints Further Implicate Market in Pandemic’s Origins

Trending

Adélie penguin family

Penguins Are Among the World’s Slowest-Evolving Birds: Study

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Image of futuristic technology such as artificial intelligence with a graphic of a robotic bird against a blue background.

An AI-Powered Scientist Proposes a Treatment for Blindness

A group of newborn mice with their mother.

Maternal Iron Deficiency Can Trigger Sex Reversal in Mouse Embryos

Multimedia

Conceptual 3D illustration of mycoplasma colonies

Taking Control of Cellular Contamination with PCR Testing

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Conceptual image of gene sequencing showing multicolored bands in a spiral arrangement on a black background.

Rare Disease Research Gets a Boost from Automated NGS Solutions

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Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue
Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

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Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
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Seeing and Sorting with Confidence

BD
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Streamlining Microbial Quality Control Testing

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Products

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

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Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

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How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis