The Brain on Anesthetics

Recording brain activity as patients are anesthetized for surgery, researchers identify a pattern that may signal loss of consciousness.

Written byBeth Marie Mole
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Wikimedia, Gordana Adamovic-MladenovicThe neuroscience of unconsciousness just became a little clearer. Recording brainwaves via electrodes embedded in the brains of human patients at the precise moment that a common, general anesthetic knocked them unconscious, researchers found that neuron activity switched from rapid, cross-brain chatter to slow, uncoordinated waves of firing.

The study, published today (November 5) in Proceedings of the National Academy of Sciences, supports a link between consciousness and coordinated communication in the brain, said Mélanie Boly of the Belgian National Fund of Scientific Research, who was not involved in the study. “When you really look at the fine-grain dynamics of the [neural] networks, you can see that the slow oscillation”—which appears at the moment consciousness is lost—“is disrupting brain connectivity,” she said, and those oscillations could one day be used in the clinic to monitor the unconsciousness of patients under anesthetics.

In the study, a team of researchers, measured neuron activity in three epileptic patients, who’d had electrodes implanted in their brains to help doctors understand what was causing their seizures. Each patient ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies