The Search for Methods to Monitor Brain Cooling

Newborns deprived of oxygen have their temperatures lowered to protect against brain damage, but it’s hard to decipher the babies’ immediate response to the intervention.

Written byKerry Grens
| 4 min read

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BRAIN STORMS: Looking like weather maps on the evening news, these graphs depict the amount of coherence between neuronal function and blood flow (NVC). An HIE baby that received cooling therapy showed greater coupling (left, red blobs), while a baby whose brain was damaged despite cooling therapy showed less (right).SCIENTIFIC REPORTS, 7:45958, 2017

Until a little more than a decade ago, doctors had few options to treat newborns whose brains were deprived of oxygen or blood at birth, a condition known as perinatal hypoxic-ischemic encephalopathy, or HIE. If babies could be stabilized and kept breathing, physicians and nurses could offer only supportive care and had to watch and wait to see how much brain damage their patients would suffer. “This was a disease where we had no treatment that worked, and [around] 60 percent of these babies were either dying or had a disability,” says Rosemary Higgins, a program scientist at the National Institute of Child Health and Human Development.

In 2005, research findings reshaped the field. Higgins and other neonatologists reported the results of a couple of ...

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Meet the Author

  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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