Three-dimensional model of the yeast genome with each chromosome colored differently.DR. MIRELA ANDRONESCU
1. New anti-malaria target
Many companies are trying to overcome malaria-drug resistance by targeting the malaria parasite’s plant-derived organelle, whose function is unknown but is for the parasite’s survival. Now researchers showed that the organelle produces isopentyle pyrophosphate (IPP), a precursor to a number of molecules vital for the parasite’s success during the blood phase. The study could have major implications for the development of anti-malarial drugs. E. Yeh, J.L Derisi, “Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum,” PLoS Biol, 9(8):e1001138, 2011. Free F1000 Evaluation
2. Yeast genome, now in 3-D In this breakthrough paper, published in May 2010, researchers unveiled the most detailed three-dimensional model of a eukaryotic genome to date—that of Saccharomyces cerevisiae. The model ...
