ADRIAN SANBORN, EREZ LIEBERMAN AIDENAn international team has completed the highest-resolution map yet of how nuclear DNA forms loops to fit inside the cell. The work was published in Cell this week (December 11).
This latest map is “a landmark in the field of genome architecture,” said the University of California, San Diego’s Bing Ren, who was not involved in the work.
“This huge dataset will be used as a highly valuable resource for many researchers to mine and address all sorts of questions related to the functioning of our genome,” added Wouter de Laat of the Hubrecht Institute in the Netherlands, who also did not participate in the study.
PETER D. TONGEResearchers in Canada and their international colleagues have reprogrammed a new type of stem cell, called “F-class,” which can differentiate into all three embryonic precursor tissues but differs from other induced pluripotent stem cells. The team described these cells in Nature this week (December 10).
“In some ways, F-class cells are a prototype of stem cells for disease research and therapeutic approaches: they grow faster and under simpler conditions ...
