Skip to main content

Week in Review: September 22–26

Assessing PubPeer’s legal threat; how lengthy ICU stays impact the gut microbiome; gene links exercise to reduced depression risk; epigenetics of innate immunity; Ebola updates

Written byTracy Vence
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00

The lawyer of a pathologist threatening to sue PubPeer users said anonymous comments cost his client a job. PubPeer has also obtained legal counsel and is preparing for the possibility of a lawsuit.

ALEXANDER ZABORINLengthy stints in intensive care units alter the gut microflora, according to a study published in mBio this week (September 23). When a patient spends a long time in ICU, “the gut undergoes near-complete ecologic collapse,” study coauthor John Alverdy, a gastrointestinal surgeon and researcher at the University of Chicago’s Pritzker School of Medicine, told The Scientist.

WIKIMEDIA, CHRISTOPH BOCKMembers of the European BLUEPRINT initiative outlined pathways crucial to macrophage training in three epigenetic analyses published in Science this week (September 25). The researchers “did a very thorough transcriptomic and epigenomic analysis of these cells and . . . they uncover not just immunologic pathways, which would be expected, but also, interestingly, some metabolic pathways that may be important to the different immunologic phenotypes of these cells,” Ofer Levy of Boston Children’s Hospital and Harvard Medical School who was not involved in the studies told The Scientist.

Without knowing how microbes in the soil contribute to atmospheric carbon, researchers are unclear how they impact—and are impacted by—climate change.

WIKIMEDIA, JEPOIRRIER (FLICKR)Researchers from the Karolinska Institute in Sweden pinpointed how a muscle gene associated with the metabolite kynurenine, which can cross the blood-brain barrier, relieves symptoms of depression in exercising mice. Their work was published in Cell this week (September 25).

“This is a very interesting study about the non-pharmacologic mechanisms of antidepressant action, a topic that’s not addressed very much,” neuroscientist ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays