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Report shows that 85% of scientists who leave Germany eventually come home again

Congressional panel critical of NIH's report on consulting and conflicts of interest

Roundup Ready wheat development discontinued in the face of Wheat Board opposition

Australian science and research groups win another 5 years of security in annual budget

Prominent Canadian researcher authored study on benefits of multivitamins

Ban on importing new embryonic cell lines hurts international work, leading scientist says

Estimated number of people in 2003 who lacked access to sanitation:2.4 billionEstimated number of people in 2003 who depended on groundwater:2 billionProjected cost per year of providing worldwide water access by 2015:$30 billionNumber of countries that experienced serious water shortages by the mid-1990s:about 80 (comprising about 40% of the world’s population)Amount of bottled water produced in 2001:1.31 million liters, up from 1.2 million liters in 2000Group that consumed the most bottl

Courtesy of Cantley labIn the mid 1980s we discovered a phosphatidylinositol kinase that co-purified with several oncoproteins and that correlated with cell transformation. When my graduate student Malcolm Whitman presented his results at a lab meeting, I noticed that in this autorad, the phosphatidylinositol phosphate produced by the oncoprotein-associated PI kinase (Type I) migrated slightly more slowly in thin layer chromatography (TLC) than that produced by PI 4-kinase (Type II).The reproduc

DRY EARTH:Photo by Roger Lemoyne/LiaisonA woman sits on the ancient steps that once led down to Lake Rajsamand near Udaipur, India. The lake dried up in 2000 due to drainage of its feeder rivers for agricultural purposes and drought.Eli Raz, an Israeli geologist, found himself in something of a hole, and a rather deep one. He had stopped his car on a desert highway near his home by the Dead Sea to inspect some rock formations. As he was walking a few hundred meters from the road, he felt a rumbl

Brad FitzpatrickA group of slow-witted, mutant mice and a protein called RIM1α may provide insight into learning and memory mechanisms. University of Texas Southwestern researchers showed that knockout mice missing RIM1α, a presynaptic protein previously studied in vitro, performed worse at learning and memory tasks than did two other sets of genetically altered mice, each a mutant for proteins involved in neurotransmitter release.1The oft-studied molecular players in learning and memo

Courtesy of Cesare BrizioResearchers say they have safely delivered therapeutic agents into mammalian cells by attaching them to insect-derived peptides. The technique may help overcome the difficulties in getting vaccines and drugs into cells where they're needed. The Wistar Institute's Laszlo Otvos, Jr., and colleagues found that pyrrhocoricin, an antimicrobial peptide originally isolated from the European sap-sucking insect, Pyrrhocoris apterus, entered the cells without damaging them.An arti

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.L.T. Vassilev et al., "In vivo activation of the p53 pathway by small-molecule antagonists of MDM2," Science, 303:844–8, Feb. 6, 2004.This paper is important because it challenges the conventional wisdom that protein-protein interactions are poor drug targets. p53 ... is inhibited when bound by MDM2. ... It is possible to disrupt the p53-MDM2 int