Apple peels give mice muscle power

A waxy substance, ursolic acid, found in high concentrations in apple peels, can help mice build muscle and reduce muscle atrophy, body fat, blood sugar levels, and cholesterol, reports Newswise.

Written byJessica P. Johnson
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Mighty MouseFROM THE MOVIE "WOLF! WOLF!" VIA NONSTOP.COM

A waxy substance, ursolic acid, found in high concentrations in apple peels, can help mice build muscle and reduce muscle atrophy, body fat, blood sugar levels, and cholesterol, reports Newswise. Researchers at the University of Iowa decided to test ursolic acid in living mice after comparing gene expression in atrophied muscle cells to cultured muscle cell lines exposed to a variety of different chemical compounds. They found that ursolic acid caused the opposite pattern of gene expression to that exhibited by atrophying cells. Currently, there is no medicine to treat muscle atrophy, which affects most people at some point in their lives, especially during illness, aging, or after nerve damage. Ursolic acid appears to improve the ability of insulin and insulin-like growth factor-1 to bind ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research