Bridging a Gap in the Brain

Neuroscientists identify how the left and right hemispheres of the mammalian brain connect during development.

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FLICKR, JOSEPH ELSBERND

Researchers have discovered key steps in the development of the corpus callosum, a cable of neurons connecting the two hemispheres of the brain, according to a paper published this week (October 10) in Cell Reports. The finding helps pin down the cellular basis of callosal agenesis, a condition in which the corpus callosum does not form properly.

“Very little is known about the cause of callosal agenesis, and there hasn’t been a satisfactory explanation for how it occurs,” study coauthor Ilan Gobius of the University of Queensland in Australia said in a press release. “We believe we’ve finally discovered one of the major causes for this group of disorders.”

Early in development, the right and left halves of the brain are separated by a fissure ...

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