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Rendering of a light blue NLRP3 inflammasome against a black background
Inflammation in Brain’s Immune Cells Triggers Depressive Behavior in Mice
In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.
Inflammation in Brain’s Immune Cells Triggers Depressive Behavior in Mice
Inflammation in Brain’s Immune Cells Triggers Depressive Behavior in Mice

In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.

In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.

astrocyte
outline of a brain slice with white patch surrounded by teal
Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study
Patience Asanga | Oct 5, 2022 | 3 min read
Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.
Two oligodendrocyte progenitor cells are being generated from adult stem cells nestled on the surface of brain ventricle
Scientists Discover “Gorditas” and Other Novel Brain Cell Types
Amanda Heidt | Jun 10, 2021 | 5 min read
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.
A reprogrammed astrocyte that can regenerate functional neurons.
Reprogramming Astrocytes: Unlocking DLX2’s Potential to Mend the Brain
Nele Haelterman, PhD | 3 min read
Scientists discover how to convert the brain’s glial cells into multipotent neural stem cells.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Infographic: How Cytokines Flow into and out of the Brain
Ashley Yeager | Oct 1, 2020 | 2 min read
Several routes exist for immune cells to communicate with neurons in the central nervous system, though T cells rarely come in direct contact with neural tissue.
Astrocytes, Not Just Neurons, Play a Role in Sleep
Abby Olena, PhD | Sep 24, 2020 | 4 min read
In mice, the brain’s main glial cell type exhibits distinctive patterns of activity across the sleep-wake cycle and influences the response to sleep deprivation.
Mitochondria from Different Brain Cells Have Different Proteins
Jef Akst | Dec 1, 2019 | 3 min read
Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences.
Infographic: What’s in a Mitochondrion?
Jef Akst | Dec 1, 2019 | 1 min read
A study finds variations in the levels of proteins for some important processes among organelles from different brain cells.
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018 | 4 min read
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018 | 10 min read
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017 | 2 min read
The acute pain that results from injury or disease is very different from chronic pain.
Glia Guru
Anna Azvolinsky | May 1, 2017 | 9 min read
Ben Barres recast glial cells from supporting actors to star performers, crucial for synaptic plasticity in the brain and for preventing neurodegenerative disorders.
Bridging a Gap in the Brain
Ben Andrew Henry | Oct 12, 2016 | 1 min read
Neuroscientists identify how the left and right hemispheres of the mammalian brain connect during development.
Brain Prize Winners Announced
Catherine Offord | Mar 3, 2016 | 2 min read
Three UK neuroscientists jointly win the €1 million European Brain Prize for their work on memory.
Adjustable Brain Cells
Ruth Williams | Feb 18, 2016 | 3 min read
Neighboring neurons can manipulate astrocytes. 
Neurons from Glia In Vivo
Kerry Grens | Oct 19, 2015 | 2 min read
Scientists present new recipes for directly converting glial cells to neurons in mouse brains.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.
Image of the Day: Amazing Astrocytes
The Scientist Staff | May 19, 2015 | 1 min read
They aren't neurons, but in rats, glial cells in the brain called astrocytes (red) play a major role in repetitive motions like chewing and breathing.
Leptin’s Effects
Kerry Grens | Jun 2, 2014 | 1 min read
The hormone leptin, which signals fullness to animals, acts not only through neurons but through glia, too.
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