Scientists Discover “Gorditas” and Other Novel Brain Cell Types

A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.

amanda heidt
| 5 min read
Two oligodendrocyte progenitor cells are being generated from adult stem cells nestled on the surface of brain ventricle

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ABOVE: Newly identified oligodendrocyte progenitor cells (green) in a mouse brain arise from adult stem cells (blue). Here, one sits on the surface of the ventricle wall, nestled among cilia (red).
ANA DELGADO AND FIONA DOETSCH, BIOZENTRUM, UNIVERSITY OF BASEL

Scientists have discovered two types of glial cells in the brains of adult mice—an astrocyte and an oligodendrocyte progenitor cell—after nudging neural stem cells to rise from dormancy, according to a study published June 10 in Science. The results suggest new roles for glial cells, best known for providing support to neurons, and could prompt a better understanding of how brains remain plastic into adulthood, when the vast majority of neurons no longer undergo cell division.

This study is “a very important addition to the whole story about these fascinating [stem] cells that exist in the adult brain of rodents that have the capacity to generate new cells,” says Arturo Alvarez-Buylla, ...

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Meet the Author

  • amanda heidt

    Amanda Heidt

    Amanda was an associate editor at The Scientist, where she oversaw the Scientist to Watch, Foundations, and Short Lit columns. When not editing, she produced original reporting for the magazine and website. Amanda has a master's in marine science from Moss Landing Marine Laboratories and a master's in science communication from UC Santa Cruz.
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