mouse brain

Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.

A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.

See some of the coolest images recently featured by The Scientist.

In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.

Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.

Mice with overactive LINE-1 retrotransposons in their brains exhibit movement difficulties, suggesting the genetic elements may play a role in ataxia in humans. 

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.

Using stem cells and a bioreactor, researchers generated living embryos that survived for more than a week and began to develop internal organs.

Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

Mice have neurons that connect to both eyes but only propagate the signal from one or the other, simplifying the information sent to the cerebral cortex.

Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.

A mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.

In both a mouse model and the hospital records of more than 3 million children, researchers found a connection between strong immune activation in males and later symptoms of autism spectrum disorder.

Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.

RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.

A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.

A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.

A study that compared several anesthetic regimens in rodents showed that only one—inhaled isoflurane—wasn’t detrimental to the activity of neurons in the hippocampus.