Infographic: What’s in a Mitochondrion?

A study finds variations in the levels of proteins for some important processes among organelles from different brain cells.

Written byJef Akst

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Isolating mitochondria from three cell types of the mouse cerebellum allowed researchers to look for differences in the organelles’ proteomes based on their cell type of origin. The experiments found many proteins that were differentially expressed in the mitochondria of Purkinje cells, granule cells, and astrocytes. Follow-up in vitro assays and in vivo imaging supported some of the functional implications of the proteomic findings.

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Jef Akst is the managing editor of The Scientist. Email her at jakst@the-scientist.com.

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Meet the Author

Jef Akst
Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.
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