Markers of Alzheimer's

Nurturing ideas to fruition, like growing plants, is a complex process that relies on a suitable substrate and favorable growth conditions.

Physicists, geneticists, computer scientists, and biologists are working together to gain a full appreciation of the intricacies of organismal growth and form.

Meet some of the people featured in the December 2019 issue of The Scientist.

Take a break from the bench to puzzle and peruse.

As the afternoon breezes blow harder in the Atacama Desert—a place so desolate it’s used as a model of Mars—more microbes move into its driest regions.

Using a tiny thermometer, researchers record fluctuations of more than 7 Kelvin in sea slug neurons when a heat-generating mitochondrial process is switched on.

Habits such as napping might influence how humans cope with extreme environments, such as those at a polar research facility in winter.

Researchers plan an oceanographic expedition to understand why a phytoplankton bloom developed as molten lava flowed into the sea east of Hawaii's Big Island.

Does science describe experience or truth?

Selected Images of the Day from the-scientist.com

Speaking a common language is key to a well-integrated team, but guidance is sparse on what—if anything—principal investigators should do about it.

Frederik Ruysch’s collections blended specimens for scientific discovery with macabre art.

The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.

The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.

The drug, called memantine, could enter clinical trials to determine its effectiveness in humans.

A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.

Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences.

A look at some of the circulating molecules that may indicate various Alzheimer’s pathologies and serve as the bases of noninvasive tests for the disease.

A novel system for customizable DNA-hydrogel manipulations

What do scientists know about this membraneless nuclear body discovered less than two decades ago?

A study finds variations in the levels of proteins for some important processes among organelles from different brain cells.

DNA-responsive polymer gels used for releasing drugs, encapsulating cells, and much more now have greater adaptability thanks to the Cas12a nuclease.