Sergiu Pasca Builds Brains to Study Developmental Disease

The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.

Written byEmily Makowski
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

ABOVE: © Golnaz Shahmirzadi Photography

As a boy growing up in Romania, Sergiu Pasca watched dictator Nicolae Ceausescu’s wife Elena on television, wearing a lab coat and talking to scientists about chemistry experiments. Elena had no scientific training and was Romania’s premier chemist in name only, but Pasca was captivated. “As a kid, I just loved the idea that she was talking about experiments every single day and discovering something new,” he says.

Inspired, he focused on chemistry in school, won several chemistry competitions, and earned a full scholarship to medical school. While many of his classmates went on to top universities in other countries, he couldn’t. “I didn’t speak English very well,” Pasca, now a stem cell researcher at Stanford University in California, tells The Scientist. “I couldn’t really take the SAT. I couldn’t take the TOEFL [Test of English as a Foreign Language]. I was not scoring; I ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs

Products

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

Parse Logo

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform