Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
Stem Cell Lines Riddled With Undetected Mutations
Stem Cell Lines Riddled With Undetected Mutations

Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.

Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.

iPSCs
a mockup of an at-home COVID-19 test in development
Top Technical Advances of 2020
Shawna Williams | Dec 18, 2020
The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.
Sergiu Pasca Builds Brains to Study Developmental Disease
Emily Makowski | Dec 1, 2019
The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.
A Brief History of Stem Cells
Scientific Breakthroughs with Stem Cells
Nele Haelterman, PhD
Discover the various ways scientists bolster stem cells to understand and cure disease.
Lindsay Hanford, Geoff B Hall
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
Vision Restored: The Latest Technologies to Improve Sight
Anna Azvolinsky | Apr 10, 2018
Cell implants, gene therapy, even optogenetics are making headway in clinical trials to treat various forms of blindness.  
Evangelos Kiskinis describes how the patient-derived iPSCs model of epilepsy help predict drug resistance.
The Scientist Speaks - Modeling Epilepsy in a Dish Using Patient-Derived iPSCs
Sejal Davla, PhD
Evangelos Kiskinis describes how the patient-derived iPSCs model of epilepsy help predict drug resistance.
Researchers Make Knockout Stem Cell Lines in One Step
Ruth Williams | Dec 1, 2017
Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.
Infographic: Combo Method of Stem Cell Generation
Ruth Williams | Nov 30, 2017
Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.
800x560-nov-23-2021
A Guide for High-Throughput Screens with Pluripotent Stem Cells
The Scientist Creative Services Team in collaboration with Miltenyi Biotec
Experts discuss reliable high-throughput workflows for PSC-derived cellular screens
Suicide Switch for Transplanted Stem Cells
Abby Olena | Mar 2, 2017
Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
Technique Talk: Supporting Organoid Growth in 3D Cell Culture
The Scientist Creative Services Team in collaboration with Bio-Techne
In this workshop, you will learn how to optimally culture organoids and support their growth after genetic manipulation.
Thirty Years of Progress
The Scientist Staff | Oct 1, 2016
Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Technique Talk: 2D Stem Cell Culture
The Scientist Creative Services Team
In this workshop, you will learn tips and tricks for culturing stem cells in 2D.
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
Kelly Rae Chi | Sep 1, 2016
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
Review: The End of Sex
Tanya Lewis | May 13, 2016
Legal expert Henry Greely envisions a world in which advances in biotechnology obviate the need for sexual reproduction as we know it.
CRISPR Technologies for the New Era of Cell and Gene Therapy
The Scientist Creative Services Team
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
Skin Cells Turned Into Immature Sperm
Tanya Lewis | Apr 29, 2016
The reprogrammed germ-like cells were unable to fertilize eggs, however.