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An illustration of the human brain made from a rainbow of colors.
Exploring the Past, Present, and Future of Brain Organoids 
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Exploring the Past, Present, and Future of Brain Organoids 
Exploring the Past, Present, and Future of Brain Organoids 

Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.

Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.

autism spectrum disorder

Histology showing IL-6 expression
Immune Molecule Alters Cellular Makeup of Human Brain Organoids
Charles Q. Choi, Spectrum | Apr 17, 2023 | 4 min read
The changes may help explain the link between maternal infection and autism, though more research is needed.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
<em >The Scientist</em>&rsquo;s Journal Club: Olfaction and the Brain
The Scientist’s Journal Club: Olfaction and the Brain
The Scientist | 1 min read
Gonzalo Otazu will discuss how the brain processes smells differently in neurotypical mice compared to a mouse model of autism spectrum disorder.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Panels showing different kinds of microglia
Mapping Tool Reveals Microglia’s Shape-Shifting Secrets
Angie Voyles Askham, Spectrum | Dec 14, 2022 | 4 min read
The approach could help test hypotheses about how atypical function of the brain’s immune cells contributes to autism.
The Scientist Speaks Podcast - Episode 12
The Scientist | 1 min read
Decoding Smell: Demystifying Human Disease and Behavior
pregnant belly clad in hospital gown with IV line going into hand
Registry Review Casts Doubt on Causal Link Between Maternal Infection and Autism
Charles Q. Choi, Spectrum | Sep 26, 2022 | 4 min read
Maternal infection during pregnancy may be associated with autism, as previous studies have suggested—but perhaps not in a causal way.
A pregnant woman gets her blood pressure checked by a doctor
U.K. Health Authority Investigates Epilepsy Drug’s Link to Autism
Peter Hess, Spectrum | Aug 30, 2022 | 3 min read
The Medicines and Healthcare products Regulatory Agency’s investigation comes after a study showed prenatal exposure to topiramate roughly triples a child’s likelihood of having autism or intellectual disability.
The Scientist Speaks Podcast - Episode 7
The Scientist | 1 min read
Brains in the Palm of your Hand: 3D Organoid Cell Culture
Colorful DNA strands
Scans of Sundry Variant Types Uncover Autism-Linked Genes
Chloe Williams, Spectrum | Aug 19, 2022 | 5 min read
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
smiling woman with hands on hips with blackboard in background
In Deep Water With Gül Dölen
Peter Hess, Spectrum | Aug 4, 2022 | 10 min read
A researcher’s existential crisis led to a scientific breakthrough.
The Scientist Speaks Podcast - Episode 1
Niki Spahich, PhD | 1 min read
Birds on the Brain: The Neuroscience Behind Songbird Communication and Human Speech
illustration of brain with DNA strand coming out the top
Genetic Underpinnings of Brain Activity May Differ in Autism
Emily Harris, Spectrum | Jul 19, 2022 | 3 min read
A study finds that expression levels of certain genes that track with brain activity—particularly those involved in brain development—vary between people with autism and their non-autistic peers.
illustration of a branching neuron
Different Forms of Autism Have Opposite Problems with Brain Precursor Cells
Charles Choi | Jun 13, 2022 | 3 min read
Compared with cells taken from non-autistic controls, neural precursors from autistic boys proliferated in atypical ways, a small study finds.
illustration of a brain divided into 4 puzzle pieces
Why Autism Therapies Have an Evidence Problem
Rachel Zamzow | Apr 14, 2022 | 7 min read
Some experts argue that better trials are needed before putting interventions into practice.
illustration of multiple brain scan images
Power Shortages Dim Results of Many Neuroimaging Studies
Angie Voyles Askham, Spectrum | Mar 17, 2022 | 4 min read
Low participant numbers render the results of many studies based on brain scans unreliable, an analysis finds.
Illustration of scientists collaborating
How to Bring the Public into the Scientific Process
Amanda Heidt | Mar 14, 2022 | 10+ min read
A new wave of research is recruiting patients and other members of the public to serve as equal partners, bringing fresh perspectives to research on diseases and other conditions.
illustration of neurons in blue with synapses lighting up
Gut Molecule Linked to Decreased Myelination in Mouse Brains
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.
Deborah Nickerson
Genome Pioneer Deborah Nickerson Dies at 67
Amanda Heidt | Feb 9, 2022 | 3 min read
The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.
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