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The mitochondria inside of a neuron are shown in red. The neurons protrusions called dendritic spines are shown in cyan.
How Mitochondria Stay Still in Neurons
An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 
How Mitochondria Stay Still in Neurons
How Mitochondria Stay Still in Neurons

An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 

An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 

mitochondria

Fatty Feasts May Come at an Immune Cost
Shelby Bradford, PhD | Jan 25, 2024 | 4 min read
Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.
Infographic showing the multifaceted role of mitochondria
Infographic: Mitochondria, the Cellular Processors
Danielle Gerhard, PhD | Dec 4, 2023 | 1 min read
Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of mitochondria.
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist | 1 min read
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
Cross-section of a blue and purple mitochondrion.
Rebranding Mitochondria
Danielle Gerhard, PhD | Dec 4, 2023 | 4 min read
As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.
Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Chiara Zurzolo and Ranabir Chakraborty stand next to a computer monitor displaying a microscopy image
Microglia Rescue Aggregate-Burdened Neurons
Charlene Lancaster, PhD | Jun 12, 2023 | 4 min read
Researchers discover that neurons trade protein aggregates for microglial-derived mitochondria through tunneling nanotubes. 
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
Photo of Chantell Evans
Chantell Evans Tracks Mitochondrial Cleanup in Neurons
Holly Barker, PhD | Dec 1, 2022 | 3 min read
The Duke University cell biologist uses live-cell microscopy to reveal how brain cells rid themselves of damaged mitochondria and what goes wrong in neurodegenerative disease.
illustration of human oocyte
Mammalian Oocytes Store mRNA in Newly Found Membraneless Structure
Alejandra Manjarrez, PhD | Oct 20, 2022 | 3 min read
The findings answer the longstanding question of where these cells hold the mRNA needed to cope with the transcriptional halt preceding meiosis.
illustration of DNA strands
Mitochondrial DNA Sneaks into Nuclear Genome
Holly Barker, PhD | Oct 17, 2022 | 3 min read
Genetic material pilfered from mitochondria may seal cracks in our genetic code, a study suggests.
The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Amanda Heidt | Oct 17, 2022 | 10+ min read
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
Illustration showing the path result of Eukaryogenesis
Infographic: Evolutionary Leaps Leading to Modern Eukaryotes
Amanda Heidt | Oct 17, 2022 | 2 min read
A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery.
A false color transmission electron microscope micrograph showing the nuclear envelope, the rough endoplasmic reticulum, the nucleus, and the cytoplasm.
New Gene Mutants Identified in Rare Motor Neuron Diseases
Clare Watson | Oct 17, 2022 | 2 min read
The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.
Neurons in all sorts of different colors, some glowing
How Fear Restructures the Mouse Brain
Natalia Mesa, PhD | Aug 15, 2022 | 4 min read
By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.
dark image with red ring
How Immature Egg Cells in Ovaries Resist Aging
Shafaq Zia | Aug 4, 2022 | 3 min read
The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.
An illustration of a mitochondrion, represented by a purple and orange bilayer, synthesizing reddish molecules of ATP.

Mitochondrial Protein Fuels Spread of Head and Neck Cancer 

Patience Asanga | Jul 8, 2022 | 3 min read
Head and neck cancer cells lacking the peptide involved in energy production were less likely to metastasize in mice.
A microscope image of Legionellales bacteria infecting a protozoan
Ancestral Bacteria May Have Invaded Early Eukaryotic Cells
Clare Watson | Jun 1, 2022 | 2 min read
The discovery that a group of cell-infecting bacteria lived roughly 2 billion years ago stirs a longstanding controversy around which came first: phagocytosis or mitochondria.
Illustration of blue shiny mitochondria
Worms Live Longer with Mitochondria Powered by Light: Preprint
Alejandra Manjarrez, PhD | May 24, 2022 | 4 min read
Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.
illustration of purple mitochondrion within a cell
Rogue Mitochondria Turn Hermaphroditic Snails Female: Study
Patience Asanga | May 19, 2022 | 3 min read
The accidental finding marks the first time a phenomenon called cytoplasmic sterility, known to occur in plants, has been found in animals.
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