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3D Illustration of a DNA molecule breaking apart into red pieces.
Mitochondria May Have Been Wrongly Accused in DNA Damage
Reactive oxygen species cause mutations to DNA bases that can lead to cancer, but the long-blamed mitochondria could have been wrongfully charged.
Mitochondria May Have Been Wrongly Accused in DNA Damage
Mitochondria May Have Been Wrongly Accused in DNA Damage

Reactive oxygen species cause mutations to DNA bases that can lead to cancer, but the long-blamed mitochondria could have been wrongfully charged.

Reactive oxygen species cause mutations to DNA bases that can lead to cancer, but the long-blamed mitochondria could have been wrongfully charged.

mitochondria

On the left, a diagram of a fetus and placenta inside the abdomen of a pregnant person, on the right, a pink mitochondrion.
Mitochondria: The Powerhouse of the Placenta
Hannah Thomasy, PhD | Jul 1, 2024 | 2 min read
Scientists seek citizens’ help to survey placental mitochondria in complicated and healthy pregnancies.
A 3D microscopic image of a heart tissue section with cardiac myocytes and macrophages.
Taking Out the Trash: An Alternative Cellular Disposal Pathway
Charlene Lancaster, PhD | Jun 6, 2024 | 4 min read
Researchers reveal that cellular secretion removes defective mitochondria when lysosomes are dysfunctional.
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist | 1 min read
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
The feet of several runners wearing brightly colored shoes.
How Exercise Sparks, then Soothes, Inflammation
Rachael Moeller Gorman | May 15, 2024 | 4 min read
Regulatory T cells in muscles surge after exercise, quelling inflammation, protecting mitochondria, and enhancing performance.
The mitochondria inside of a neuron are shown in red. The neuron’s protrusions called dendritic spines are shown in cyan.
How Mitochondria Stay Still in Neurons
Mariella Bodemeier Loayza Careaga, PhD | Mar 13, 2024 | 5 min read
An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 
Fatty Feasts May Come at an Immune Cost
Shelby Bradford, PhD | Jan 25, 2024 | 4 min read
Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.
Infographic showing the multifaceted role of mitochondria
Infographic: Mitochondria, the Cellular Processors
Danielle Gerhard, PhD | Dec 4, 2023 | 1 min read
Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of mitochondria.
Cross-section of a blue and purple mitochondrion.
Rebranding Mitochondria
Danielle Gerhard, PhD | Dec 4, 2023 | 4 min read
As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.
Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Chiara Zurzolo and Ranabir Chakraborty stand next to a computer monitor displaying a microscopy image
Microglia Rescue Aggregate-Burdened Neurons
Charlene Lancaster, PhD | Jun 12, 2023 | 4 min read
Researchers discover that neurons trade protein aggregates for microglial-derived mitochondria through tunneling nanotubes. 
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
Photo of Chantell Evans
Chantell Evans Tracks Mitochondrial Cleanup in Neurons
Holly Barker, PhD | Dec 1, 2022 | 3 min read
The Duke University cell biologist uses live-cell microscopy to reveal how brain cells rid themselves of damaged mitochondria and what goes wrong in neurodegenerative disease.
illustration of human oocyte
Mammalian Oocytes Store mRNA in Newly Found Membraneless Structure
Alejandra Manjarrez, PhD | Oct 20, 2022 | 3 min read
The findings answer the longstanding question of where these cells hold the mRNA needed to cope with the transcriptional halt preceding meiosis.
illustration of DNA strands
Mitochondrial DNA Sneaks into Nuclear Genome
Holly Barker, PhD | Oct 17, 2022 | 3 min read
Genetic material pilfered from mitochondria may seal cracks in our genetic code, a study suggests.
The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Amanda Heidt | Oct 17, 2022 | 10+ min read
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
Illustration showing the path result of Eukaryogenesis
Infographic: Evolutionary Leaps Leading to Modern Eukaryotes
Amanda Heidt | Oct 17, 2022 | 2 min read
A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery.
A false color transmission electron microscope micrograph showing the nuclear envelope, the rough endoplasmic reticulum, the nucleus, and the cytoplasm.
New Gene Mutants Identified in Rare Motor Neuron Diseases
Clare Watson | Oct 17, 2022 | 2 min read
The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.
Neurons in all sorts of different colors, some glowing
How Fear Restructures the Mouse Brain
Natalia Mesa, PhD | Aug 15, 2022 | 4 min read
By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.
dark image with red ring
How Immature Egg Cells in Ovaries Resist Aging
Shafaq Zia | Aug 4, 2022 | 3 min read
The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.
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