Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.

Neanderthal DNA surprises in modern humans, the first blood test for Alzheimer’s, a discovery of new human salivary glands, and, oh yeah, a pandemic

An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.

A complete bird specimen uncovered in northeastern Siberia is radiocarbon dated to be roughly 44,000–49,000 years old.

The findings could represent a novel mechanism for relieving inflammatory pain.

New TALEN-based tools enable the organelle’s genome to be targeted and modified.

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.

Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.

The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.

The functional, respiring organelles appear to be present in the blood of healthy people, but their function is yet unclear.

A single-celled organism has an energy-producing enzyme with unique features.

Using a tiny thermometer, researchers record fluctuations of more than 7 Kelvin in sea slug neurons when a heat-generating mitochondrial process is switched on.

Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences.

A study finds variations in the levels of proteins for some important processes among organelles from different brain cells.

Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.

From regulating each other’s gene expression to encoding different parts of the same proteins, the two genome types in every eukaryotic cell are far from independent.

Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.