Critical Connections

Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.

Written byKaren Hopkin
| 9 min read

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Joshua R. Sanes, Professor of Molecular and Cellular Biology, Paul J. Finnegan Family Director, Center for Brain Science, Harvard University PORTER GIFFORD

I did my thesis research during the Watergate hearings,” says Josh Sanes, who was studying the development of moth sensory neurons at Harvard in the early 1970s. “I sat in the lab cutting 1-micron sections for about a year,” he says. “I did not miss a single word.” The experience inspired him to spend some time on Capitol Hill. “I wanted to see the characters I’d been listening to on the radio,” he says.

The gig at the Office of Technology Assessment was “a gas,” says Sanes. “I got to brief Teddy Kennedy on one of my reports. That was a big thrill. I walked him all the way from the Congressional Office Building across the lawn to the hearing room.” But Sanes decided that ...

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