Mechanisms of Chili’s Heat, Menthol’s Cool Garner Nobel

David Julius and Ardem Patapoutian won this year’s Nobel Prize in Physiology or Medicine for their research on the ion channels involved in perceiving heat, cold, pain, and touch.

Written byChloe Tenn
| 4 min read
sketch of two men smiling

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ABOVE: David Julius and Ardem Patapoutian
© NIKLAS ELMEHED © NOBEL PRIZE OUTREACH

This year’s Nobel Prize in Physiology or Medicine goes to David Julius of the University of California, San Francisco, and Ardem Patapoutian of Scripps Research Institute, the Nobel Assembly announced today. The prize recognizes discoveries by the winners of receptors that allow perception of temperature, pressure, and pain.

“Their collective discoveries explain how we feel the warm sun, a cool breeze and [a] loved ones touch,” writes Alexander Chesler, an NIH investigator who completed his postdoc with Julius, in a Twitter message to The Scientist. “They provide us with the details about how we detect dangerous stimuli. These discoveries completely changed the fields of somatosensation and pain.”

“These are fundamental discoveries in the field of physiology and it will be the beginning of a new era where we can identify drugs active in those channels,” says Eric Honore, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • young woman smiling

    Chloe Tenn is a graduate of North Carolina State University, where she studied neurobiology, English, and forensic science. Fascinated by the intersection of science and society, she has written for organizations such as NC Sea Grant and the Smithsonian. Chloe also works as a freelancer with AZoNetwork, where she ghostwrites content for biotechnology, pharmaceutical, food, energy, and environmental companies. She recently completed her MSc Science Communication from the University of Manchester, where she researched how online communication impacts disease stigma. You can check out more of her work here.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies