Dissecting the Unusual Biology of the SARS-CoV-2 Delta Variant

An ability to build up higher concentrations of viral particles in people’s airways and mutations that might boost its ability to infect human cells could be what gives the Delta variant its evolutionary edge.

katya katarina zimmer
| 8 min read
art+graph showing rise and fall of three different covid variants

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SARS-CoV-2 is fitter than ever. Its latest incarnation, the Delta (or B.1.617.2) variant, is the fastest-spreading form of the virus yet. First identified in India, which it swept through killing hundreds of thousands this spring, Delta has swiftly become the most dominant coronavirus variant worldwide. While it’s already driving rapid increases in hospitalizations and deaths—overwhelmingly in unvaccinated populations—simply by virtue of being more transmissible, it may also cause more severe disease than some previously dominating SARS-CoV-2 variants.

Meanwhile, emerging data suggest that when vaccinated people become infected with the Delta variant and develop symptoms—which, although increasing in frequency, remains exceedingly rare, officials report—they might be as contagious as unvaccinated infected people. Those findings motivated the Centers for Disease Control and Prevention (CDC) to recommend in late July that in places with high transmission of the virus, even fully vaccinated people should wear masks indoors.

The Delta ...

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Meet the Author

  • katya katarina zimmer

    Katarina Zimmer

    After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field. Following an internship with The Scientist in 2017, she has been happily freelancing for a number of publications, covering everything from climate change to oncology.
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