Drugs, Developed

In an era of instant communication, we must be careful how word of new and untested treatments is shared.

Written byBob Grant
| 3 min read
anesthesia 2019 march editorial

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ABOVE: andrzej krauze

Iam no fan of anesthesia. The feeling of being rendered unconscious to facilitate the manipulation of my body, only to be reanimated afterward, gives me, like many people (I assume), the heebie-jeebies. But alas, anesthesia is a medical necessity. It has made lifesaving surgeries and once-dreaded dental procedures pain-free and relatively routine for more than 150 years. My own medical care, not to mention that of billions of other people and animals, has benefited greatly from this chemical control of consciousness.

Beyond my personal misgivings, anesthesia’s development into a widely accepted medical protocol illustrates an interesting, if outmoded, avenue of innovation—let’s call it efficacy sans mechanism. As described here by scientists Emery Brown and Francisco Flores in their dispatch from the front lines of anesthesia research, in the mid-19th century, dentist William Morton successfully put a patient under general anesthesia (using ether vapor, in this case) in ...

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Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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Published In

March 2019

Going Under

Dissecting the effects of anesthetics

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