© LUCY CONKLIN
Obesogens, such as the extensively studied fungicide tributyltin (TBT), can act in a variety of ways to promote fat storage and adipose tissue production, often by disrupting hormonal signaling. Such effects have been well documented in animal models and in human cell culture, but the impact of these compounds on people is still unclear.
© LUCY CONKLINMice exposed to TBT end up with fat deposits in the liver and testis and greater fat mass throughout the body. These effects can perpetuate through generations, presumably via epigenetic mechanisms.
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