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Thermal image of a head and neck.
Newly Found Fat Cell Uses a Different Approach to Heat the Body  
Single-cell sequencing unpacked 10 varieties of fat cells, including one that uses an alternative heat-regulating strategy that protects against weight gain.
Newly Found Fat Cell Uses a Different Approach to Heat the Body  
Newly Found Fat Cell Uses a Different Approach to Heat the Body  

Single-cell sequencing unpacked 10 varieties of fat cells, including one that uses an alternative heat-regulating strategy that protects against weight gain.

Single-cell sequencing unpacked 10 varieties of fat cells, including one that uses an alternative heat-regulating strategy that protects against weight gain.

fat

Microscopy photo of a dissected fly ovary with mature oocytes visible as dark ovals.
How Nutrition Regulates Ovulation
Shelby Bradford, PhD | Jun 19, 2024 | 4 min read
Fly fat tissue senses nutritional status through a stress response pathway to control reproductive activities.
An international team of scientists used sensitive instruments to show that oil from human skin reacts with ozone to generate potent, free radicals. These chemicals can further react with most organic compounds present in the indoor environment to produce dangerous pollutants. 
Caught on Camera
The Scientist | Nov 14, 2022 | 3 min read
See some of the coolest images recently featured by The Scientist
Purple and white fluorescent stain of cells
How Fat Cells Help Kick Parasites Out of Mice: Study
Natalia Mesa, PhD | Oct 14, 2022 | 3 min read
Immune cells get a lot of shine when it comes to fighting infection, but it turns out that fat might be just as important for removing parasitic invaders.
Adipose tissue under the microscope appearing as red blobs on a white background
Mouse Brains Appear to Eavesdrop on Their Fat
Alejandra Manjarrez, PhD | Sep 9, 2022 | 4 min read
For the first time, a team visualizes sensory nerves projecting into adipose tissue in mice and finds these neuronal cells may counteract the local effects of the sympathetic nervous system.
A colored microscope image of a cross section of a human artery filled with fatty plaques
Protein-Recycling Process Protective Against Arterial Plaques
Clare Watson | Aug 1, 2022 | 2 min read
A team of scientists has found that in mice, a cellular housekeeping pathway protects against a major cause of heart attacks and strokes.
artist's depiction of white, beige, and brown fat cells
Heat May Melt Away White Fat
Sophie Fessl, PhD | Mar 4, 2022 | 4 min read
Local heat therapy induces browning of adipose tissue in mice and humans, a study finds, suggesting it could help treat obesity—though some experts have reservations.
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021 | 3 min read
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Fat Tissue Reorganizes During Pregnancy
Catherine Offord | Aug 1, 2021 | 3 min read
Researchers identify a protein that promotes changes in adipose tissue in vitro and in pregnant mice and may help protect against gestational diabetes in humans.
Infographic: How Pregnancy Changes Fat Tissue
Catherine Offord | Aug 1, 2021 | 1 min read
Researchers propose a mechanism by which a protein produced in the placenta may trigger blood vessel growth and enlarge fat cells.
brown fat, metabolism, cardiovascular disease, cardiometabolic disease, genetics & genomics, immunology, Q&A, adipose tissue, obesity
Q&A: Brown Fat Linked to Better Cardio and Metabolic Health
Amanda Heidt | Jan 12, 2021 | 5 min read
Paul Cohen of the Rockefeller University describes his study of thousands of people, finding that the energy-burning tissue is tied to a lower risk of for several diseases, including type 2 diabetes, high blood pressure, and heart disease.
Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Ruth Williams | Oct 15, 2020 | 3 min read
Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.
Exercising Before Eating Burns More Fat: Study
Emily Makowski | Nov 27, 2019 | 1 min read
Men had better fat-burning results when they had breakfast after cycling instead of beforehand.
circadian clock microbiome hdac3 histone deacetylation acetylation epigenetics gene expression metabolism fat lipid intestine gut
Microbes Shape Circadian Rhythms in the Mouse Gut
Kerry Grens | Sep 27, 2019 | 2 min read
The diurnal cycles of the microbiome alter the activity of a protein produced by the host, and in turn guide histone acetylation, gene expression, and metabolic activity.
gavel fda us stem cell adipose-derived
Judge Says FDA Can Stop Clinic from Selling Stem Cell Treatments
Emma Yasinski | Jun 7, 2019 | 4 min read
The decision may facilitate the agency cracking down more effectively on the unproven interventions these companies sell.
fat cells cachexia killer t cells
Cachexia Is Driven By Killer T Cells in a Mouse Model of Infection
Katarina Zimmer | May 22, 2019 | 5 min read
A new study reveals an unexpected role for the immune cells and a previously unknown mechanism for the wasting syndrome.
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
Catherine Offord | Apr 1, 2019 | 3 min read
Researchers disentangle how adipocytes communicate with prostate tumors in mice.
fat tissue can help cancer cells proliferate metastasize
Infographic: How Fat Cells Influence Tumor Growth
Catherine Offord | Apr 1, 2019 | 1 min read
Mice that lack p62 in their fat cells grow more tumors than animals that have a functioning version of the protein.
Infographic: The Omentum’s Role in Health and Disease
Selene Meza-Perez and Troy D. Randall | Oct 1, 2018 | 1 min read
Belly fat helps fight infection, but is also a common site of metastasis.
Contributors
The Scientist Staff | Oct 1, 2018 | 3 min read
Meet some of the people featured in the October 2018 issue of The Scientist.
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