Federal Investigators Probe Possible Misconduct in Pig Research

A quintet of research papers, all involving subjecting newborn piglets to brain damage, have been retracted because the data can’t be substantiated.

Written byDan Robitzski
| 2 min read
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The Office of Research Integrity, part of the Department of Health and Human Services, has confirmed to an advocacy group that it is investigating the circumstances of five now-retracted papers for possible academic misconduct. Questions surrounding the research, which involved causing brain trauma to 30 newborn piglets, are piling up, but very little in the way of explanation has been offered by the university that hosted the experiments or the journals that published them.

Between 2016 and 2019, several research papers led by then–University of Pennsylvania pharmacy researcher William Armstead on neuromolecular outcomes following traumatic brain injury were published in a handful of journals, including the Journal of Neurotrauma and Pediatric Research. The research involved administering percussive brain injuries to piglets using a piston that both displaces and deforms neural tissue, according to Retraction Watch.

Earlier this year, five of those papers, all coauthored by Armstead, who is now retired, ...

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    Dan is an award-winning journalist based in Los Angeles who joined The Scientist as a reporter and editor in 2021. Ironically, Dan’s undergraduate degree and brief career in neuroscience inspired him to write about research rather than conduct it, culminating in him earning a master’s degree in science journalism from New York University in 2017. In 2018, an Undark feature Dan and colleagues began at NYU on a questionable drug approval decision at the FDA won first place in the student category of the Association of Health Care Journalists' Awards for Excellence in Health Care Journalism. Now, Dan writes and edits stories on all aspects of the life sciences for the online news desk, and he oversees the “The Literature” and “Modus Operandi” sections of the monthly TS Digest and quarterly print magazine. Read more of his work at danrobitzski.com.

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