Aspirin and other nonsteroidal anti-inflammatory drugs reduce the risk of cancer by inducing apoptotic cell death. How this occurs, however, is unknown. A critical pathway for apoptosis involves the release of cytochrome c from mitochondria. This interacts with Apaf-1 to activate caspase proteases that orchestrate cell death. Douglas R. Green from La Jolla Institute for Allergy & Immunology, San Diego, and colleagues, found that treatment of a human cancer cell line with aspirin induced casp
Aspirin and other nonsteroidal anti-inflammatory drugs reduce the risk of cancer by inducing apoptotic cell death. How this occurs, however, is unknown. A critical pathway for apoptosis involves the release of cytochrome
Further analysis of the apoptotic event showed that aspirin induces mitochondrial release of cytochrome
These data provide evidence that the release of cytochrome c is an important ...
A citizen science game explores how social choices and networks can influence how an illness moves through a population.
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Modern DNA synthesis platforms empower researchers to explore the molecular world, from next-generation sequencing to cell and gene therapy development.
An improved chromatography membrane elution method helps scientists achieve higher yields of pure plasmid DNA.
By fine-tuning polishing conditions, scientists attain high titers of infectious lentiviral particles during purification.
Discover a scalable and flexible GMP-compliant workflow for producing plasmid DNA.
Industry-first smart HPLC system to provide authenticated user access verification on onboard touchscreen for superior security.
Setting new standards for intelligent mass detection, sensitivity, and sustainability.
Compact, Powerful, and now Mass Spec-Connected for Superior Analytical Performance
The Wellcome Sanger Institute, Helmholtz Munich, and Parse Biosciences have announced a landmark international collaboration to create a Cancer Plasticity Atlas.
