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When it comes to thwarting roundworms, scientists find that combining four antiparasitic drugs in smaller doses packs a greater punch than the four drugs alone.

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A 10-minute timelapse video of roundworms (Caenorhabditis elegans) fed either nutrient solution (top) or a combination of four antiparisitic drugs (bottom) within a microfluidic chamber.TAEJOON KONG, ISU RESEARCH LABORATORY See X. Ding et al., “Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique,” Science Advances, 3:eaao1254, 2017.

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