Infant Brain Scans May Predict Autism Diagnosis

A computer algorithm can identify the brains of autism patients with moderate accuracy based on scans taken at six months and one year of age.

Written byJef Akst
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

MRI brain scanFLICKR, ANDREW HAZLETTIn a study of nearly 150 infants and toddlers, researchers compared MRI scans of children’s brains when they were six months, one year, and two years old. A computer then processed the six-month and one-year scans and managed to correctly predict which children would go on to receive an autism diagnosis. Among children in high-risk families, the algorithm correctly identified about 80 percent of the infants that went on to develop autism, according to the study published this week (February 15) in Nature.

“It’s been a continual goal of Autism Speaks and the autism community to drive the age of diagnosis to be as early as possible,” Mathew Pletcher, interim chief science officer at Autism Speaks, which partially funded the study, told STAT News. “Early diagnosis in autism does make a difference.”

Although children can be diagnosed as early as age two, most children are not diagnosed under after they’ve turned four, or when behavioral symptoms begin to appear. “Our findings are pre-symptomatic, certainly pre-consolidation of the diagnosis,” coauthor Joseph Piven, who leads the eight-center Infant Brain Imaging Study Network, told STAT News. “That’s a giant step in the field.”

The key to the new study’s algorithm was the comparison of the six-month and one-year scans, and what ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

    View Full Profile
Share
Image of a man in a laboratory looking frustrated with his failed experiment.
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies