Infant Brain Scans May Predict Autism Diagnosis

A computer algorithm can identify the brains of autism patients with moderate accuracy based on scans taken at six months and one year of age.

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MRI brain scanFLICKR, ANDREW HAZLETTIn a study of nearly 150 infants and toddlers, researchers compared MRI scans of children’s brains when they were six months, one year, and two years old. A computer then processed the six-month and one-year scans and managed to correctly predict which children would go on to receive an autism diagnosis. Among children in high-risk families, the algorithm correctly identified about 80 percent of the infants that went on to develop autism, according to the study published this week (February 15) in Nature.

“It’s been a continual goal of Autism Speaks and the autism community to drive the age of diagnosis to be as early as possible,” Mathew Pletcher, interim chief science officer at Autism Speaks, which partially funded the study, told STAT News. “Early diagnosis in autism does make a difference.”

Although children can be diagnosed as early as age two, most children are not diagnosed under after they’ve turned four, or when behavioral symptoms begin to appear. “Our findings are pre-symptomatic, certainly pre-consolidation of the diagnosis,” coauthor Joseph Piven, who leads the eight-center Infant Brain Imaging Study Network, told STAT News. “That’s a giant step in the field.”

The key to the new study’s algorithm was the comparison of the six-month and one-year scans, and what ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
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