1. A mesh of multiple electrodes is injected toward the rear of the mouse eye, where it unfurls onto the retina.
2. Wires connected to the mesh extend from the corner of the animal’s eye to enable electrical recording of retinal activity in response to stimulation, such as bars of light shown on a screen.
While the animals are restrained, their heads immobilized, for sessions of light stimulation and recording, they are free to move and behave normally between sessions. Remarkably, the meshes have little effect on vision, and after a few weeks they detach from the retina.
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