The new technique helped pig tibias heal in just eight weeks.
© GEORGE RETSECK
To repair a fractured pig tibia, researchers inserted a collagen scaffold that attracts mesenchymal stem cells (MSCs). Two weeks later, they injected a mix of microbubbles and DNA encoding bone morphogenetic protein (BMP) at the fracture site. Finally, they applied a pulse of ultrasound to encourage the MSCs to take up the DNA, and thus begin producing BMP. Within eight weeks, the bones were healed.
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Ruth is a freelance journalist. Before freelancing, Ruth was a news editor for the Journal of Cell Biology in New York and an assistant editor for Nature Reviews Neuroscience in London. Prior to that, she was a bona fide pipette-wielding, test tube–shaking, lab coat–shirking research scientist. She has a PhD in genetics from King’s College London, and was a postdoc in stem cell biology at Imperial College London. Today she lives and writes in Connecticut.
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