Cell mobility
The basic medical research award goes to Michael Sheetz of Columbia University, James Spudich of Stanford University, and Ronald Vale of the University of California, San Francisco, for their work on cytoskeletal motor proteins, which serve a variety of cellular functions, including transporting cargo, contracting muscles, and enabling cell movement. Collectively the trio “established ways to study molecular motors in detail,” according to the Lasker announcement. Their work supported subsequent discoveries that include the motor protein kinesin and the process of using chemical energy to power the cell. “The landmark achievements of Vale, Spudich, and Sheetz are driving drug-discovery efforts aimed at cardiac problems as well as cancer,” the announcement read.
Another’s liver
The prize in the category of clinical medical research went to Thomas Starzl of the University of Pittsburgh and Roy Calne, an emeritus professor at Cambridge University, for the development of liver transplantation, once “deemed ...