April 1994

As is customary at the annual AAAS meeting, a wide variety of current science-and-society topics were addressed in the sessions. Among these were: the dangers posed by the rapid spread of drug resistance in disease-causing bacteria, the role of science fiction in presenting science to the public, and the ethical questions raised by recent research showing that some men may be genetically predisposed to homosexuality. Following is a

With health-care reform proposals threatening financial prospects, firms are shelving projects laying off researchers The biotech industry is marshaling its forces for what many of its executives view as the political fight of its life. Financial analysts and other observers agree with the executives, saying that the industry faces financial threats posed by various mechanisms in President Clinton's health plan designed to influenc

As is customary at the annual AAAS meeting, a wide variety of current science-and-society topics were addressed in the sessions. Among these were: the dangers posed by the rapid spread of drug resistance in disease-causing bacteria, the role of science fiction in presenting science to the public, and the ethical questions raised by recent research showing that some men may be genetically predisposed to homosexuality. Following is a

With health-care reform proposals threatening financial prospects, firms are shelving projects laying off researchers The biotech industry is marshaling its forces for what many of its executives view as the political fight of its life. Financial analysts and other observers agree with the executives, saying that the industry faces financial threats posed by various mechanisms in President Clinton's health plan designed to influenc

When scientists accept a nomination to become Howard Hughes Medical Institute (HHMI) investigators, they become employees of HHMI, receiving full financial support for salary, staff, and equipment in renewable appointments of three, five, or seven years. However, HHMI investigators--who conduct their work at universities and medical centers across the United States-- still maintain their institutional appointments. Under a collabo

When scientists accept a nomination to become Howard Hughes Medical Institute (HHMI) investigators, they become employees of HHMI, receiving full financial support for salary, staff, and equipment in renewable appointments of three, five, or seven years. However, HHMI investigators--who conduct their work at universities and medical centers across the United States-- still maintain their institutional appointments. Under a collabo

Agenda For U.S. AIDS Research Is Due For A Complete Overhaul Author: Robert S. Root-Berstein Date: April 4, 1994 A recent front-page article in The Scientist (F. Hoke, "National AIDS Task Force Expected To Accelerate Drug Development," Feb. 7, 1994, page 1) reported that a newly formed, United States government-backed, 15-member panel intends, among other things, to improve communication between pharmaceutical and b

Agenda For U.S. AIDS Research Is Due For A Complete Overhaul Author: Robert S. Root-Berstein Date: April 4, 1994 A recent front-page article in The Scientist (F. Hoke, "National AIDS Task Force Expected To Accelerate Drug Development," Feb. 7, 1994, page 1) reported that a newly formed, United States government-backed, 15-member panel intends, among other things, to improve communication between pharmaceutical and b

Healthy Dialogue Human Rights - Via E-mail Top Banana SSC Yard Sale Learning About Learning New Gynecology Journal A Global Warming Mystery The National Institutes of Health is presenting a free, nine-week series of "easy-to-understand, entertaining, and informative" lectures about the basics of biomedical research for the general public. Sessions--which began March 31 and take place on consecutive Thursday evenings until May 26 at

Healthy Dialogue Human Rights - Via E-mail Top Banana SSC Yard Sale Learning About Learning New Gynecology Journal A Global Warming Mystery The National Institutes of Health is presenting a free, nine-week series of "easy-to-understand, entertaining, and informative" lectures about the basics of biomedical research for the general public. Sessions--which began March 31 and take place on consecutive Thursday evenings until May 26 at

Well, if they feel that way, they're wrong. Already, health- care reform is having a damaging impact on the scientific work force--and the implications for the future are even more threatening. The CEOs of two small biotech firms and I recently met with the editorial board of the Baltimore Sun. During the meeting, one of the executives explained that, like 99 percent of United States biotechnology companies, his enterprise had no p

Well, if they feel that way, they're wrong. Already, health- care reform is having a damaging impact on the scientific work force--and the implications for the future are even more threatening. The CEOs of two small biotech firms and I recently met with the editorial board of the Baltimore Sun. During the meeting, one of the executives explained that, like 99 percent of United States biotechnology companies, his enterprise had no p

First, they reported, investigators fail to credit National Institutes of Health sponsorship of their work. Second, they noted, researchers do not clearly communicate the significance and utility of their basic findings to the advancement of medicine, the environment, or the economy. Sen. Barbara Mikulski (D-Md.), for example, views basic science efforts as "curiosity-driven activities," which she equates with pork. Members of Cong

First, they reported, investigators fail to credit National Institutes of Health sponsorship of their work. Second, they noted, researchers do not clearly communicate the significance and utility of their basic findings to the advancement of medicine, the environment, or the economy. Sen. Barbara Mikulski (D-Md.), for example, views basic science efforts as "curiosity-driven activities," which she equates with pork. Members of Cong

Rank Paper Citations 1 D.R. Rosen, et al., "Mutations in Cu/Zn 54 superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis," Nature, 362(6415):59-62, 1993. 2 G. Pantaleo, et al., "HIV infection is 53 active and progressive in lymphoid tissue during the clinically latent stage of disease," Nature, 362(6418):355-8, 1993. 3 R.B. Ren, et al., "Identification of a 47 ten-amino acid proline-rich SH3 bindin

Rank Paper Citations 1 D.R. Rosen, et al., "Mutations in Cu/Zn 54 superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis," Nature, 362(6415):59-62, 1993. 2 G. Pantaleo, et al., "HIV infection is 53 active and progressive in lymphoid tissue during the clinically latent stage of disease," Nature, 362(6418):355-8, 1993. 3 R.B. Ren, et al., "Identification of a 47 ten-amino acid proline-rich SH3 bindin

P. Dent, W. Haser, T.A.J. Haystead, L.A. Vincent, T.M. Roberts, T.W. Sturgill, "Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro," Science, 257:1404-7, 1992. Paul Dent (Department of Medicine, University of Virginia Health Sciences Center, Charlottesville): "Investigators in signal transduction want to understand in detail the molecular steps by which growth factors, hormones, and oncogene

L.S. Rothman, R.R. Gamache, R.H. Tipping, C.P. Rinsland, M.A.H. Smith, D.C. Benner, V.M. Devi, J.-M. Flaud, C. Camy- Peyret, A. Perrin, A. Goldman, S.T. Massie, L.R. Brown, R.A. Toth, "The HITRAN molecular database: Editions of 1991 and 1992," Journal of Quantitative Spectroscopy and Radiative Transfer, 48:469-507, 1992. Laurence S. Rothman (Air Force Geophysics Directorate, Phillips Laboratory, Hanscom Air Force Base, Mass.): "Most

L.S. Rothman, R.R. Gamache, R.H. Tipping, C.P. Rinsland, M.A.H. Smith, D.C. Benner, V.M. Devi, J.-M. Flaud, C. Camy- Peyret, A. Perrin, A. Goldman, S.T. Massie, L.R. Brown, R.A. Toth, "The HITRAN molecular database: Editions of 1991 and 1992," Journal of Quantitative Spectroscopy and Radiative Transfer, 48:469-507, 1992. Laurence S. Rothman (Air Force Geophysics Directorate, Phillips Laboratory, Hanscom Air Force Base, Mass.): "Most

P. Dent, W. Haser, T.A.J. Haystead, L.A. Vincent, T.M. Roberts, T.W. Sturgill, "Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro," Science, 257:1404-7, 1992. Paul Dent (Department of Medicine, University of Virginia Health Sciences Center, Charlottesville): "Investigators in signal transduction want to understand in detail the molecular steps by which growth factors, hormones, and oncogene

Abacus Concepts 1918 Bonita Ave. Berkeley, Calif. 94704 (510) 540-1949 Fax: (510) 540-0260 Advanced Systems Management 1200 S. Acadian Suite 110 Baton Rouge, La. 70806 (504) 343-7151 Fax: (504) 383-3048 BBN Software Products Corp. 150 Cambridge Park Dr. Cambridge, Mass. 02140 (617) 873-5000 Fax: (617) 873-4020 BMDP Statistical Software Inc. 1440 Sepulveda Blvd. Suite 316 Los Angeles, Calif. 90025 (310) 479-7799 Fax: (310) 312-01

Abacus Concepts 1918 Bonita Ave. Berkeley, Calif. 94704 (510) 540-1949 Fax: (510) 540-0260 Advanced Systems Management 1200 S. Acadian Suite 110 Baton Rouge, La. 70806 (504) 343-7151 Fax: (504) 383-3048 BBN Software Products Corp. 150 Cambridge Park Dr. Cambridge, Mass. 02140 (617) 873-5000 Fax: (617) 873-4020 BMDP Statistical Software Inc. 1440 Sepulveda Blvd. Suite 316 Los Angeles, Calif. 90025 (310) 479-7799 Fax: (310) 312-01

Unisyn Releases Medium For Growing Hybridomas Ashton Pumpmatic Offers Pipetting System Designed To Reduce Contamination Gelman Sciences Introduces Minispike Acrodisc Filter Database Package From Advanced Imaging Concepts Hamamatsu Corp.'s Avalanche Photodiode Perkin-Elmer Unveils New Workstation For Chromatography Nanoprobes' Gold-Probe Protein Labeling Kit Ultraviolet And Visible Transillumination Products From Hoefer Nikon's Zoom

Unisyn Releases Medium For Growing Hybridomas Ashton Pumpmatic Offers Pipetting System Designed To Reduce Contamination Gelman Sciences Introduces Minispike Acrodisc Filter Database Package From Advanced Imaging Concepts Hamamatsu Corp.'s Avalanche Photodiode Perkin-Elmer Unveils New Workstation For Chromatography Nanoprobes' Gold-Probe Protein Labeling Kit Ultraviolet And Visible Transillumination Products From Hoefer Nikon's Zoom

As it is, she plans to go on to graduate school for advanced study in pharmacology, a subject she hit upon as she cast about in the sea of different biology concentrations. But now she knows that she can call Gilmer, a cell biologist at Glaxo Inc. in Research Triangle Park, N.C., at any time for advice about her career, thanks to Sease's nomination as a Glaxo Women in Science Scholar by the major pharmaceutical firm. Sease may even

As it is, she plans to go on to graduate school for advanced study in pharmacology, a subject she hit upon as she cast about in the sea of different biology concentrations. But now she knows that she can call Gilmer, a cell biologist at Glaxo Inc. in Research Triangle Park, N.C., at any time for advice about her career, thanks to Sease's nomination as a Glaxo Women in Science Scholar by the major pharmaceutical firm. Sease may even

Two Alzheimer's Disease Researchers Are Awarded Met Life Foundation Prize Date: April 4, 1994, pp.23 Blas Frangione, a pathologist from New York University Medical Center and Allen Roses, a neurologist from Duke University Medical Center, Durham, N.C., were presented the Metropolitan Life Foundation Award for Medical Research on February 16 in Washington, D.C. Each received $200,000 toward his research and a $50,000 personal priz

Two Alzheimer's Disease Researchers Are Awarded Met Life Foundation Prize Date: April 4, 1994, pp.23 Blas Frangione, a pathologist from New York University Medical Center and Allen Roses, a neurologist from Duke University Medical Center, Durham, N.C., were presented the Metropolitan Life Foundation Award for Medical Research on February 16 in Washington, D.C. Each received $200,000 toward his research and a $50,000 personal priz