Ephemeral Life

Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.

Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

Engineered bacteria sound the alarm on a common oncogenic mutation.

As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.

A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.

Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of mitochondria.

The Cre-lox recombination method orchestrates remarkable genetic manipulations that remain a gold standard for transgenic mice.

A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings.

A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.

Removing parts of the genome is a key step in some species’ development.

During early pregnancy, the placenta remodels the uterine environment to support fetal growth

In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related neurodegenerative diseases.

Low oxygen resuscitates gene transcription after death.

In 2006, Paul Rothemund transformed the field of DNA nanotechnology when he unveiled an innovative approach for making shapes and patterns from genetic material.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

Standing at the cornerstone of genetic research, Cre-loxP recombination serves as molecular scissors for precisely manipulating the genome.

Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.

A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.

Behind every successful scientist, there is another scientist.

Put on your thinking cap, and take on this fun challenge.