Cover Story

Vaccines
Robin A. Weiss and Peter Hale | Jun 1, 2011
Looking back, looking ahead

Features

The Last Vaccine Frontier
Brad Spellberg | Jun 1, 2011
Successful vaccines have been created to protect against pathogenic bacteria and viruses. Why aren’t there any for combating fungal infections?
Recognizing the Human Potential
Gene M. Shearer and Adriano Boasso | Jun 1, 2011
It may be time to reconsider an AIDS vaccine which is more human than viral, triggering the immune system in a way that no other vaccine does.
Shooting Down Addiction
Thomas Kosten | Jun 1, 2011
A new breed of vaccines aims to wean users off cocaine.

Foundations

One-Man NIH, 1887

One-Man NIH, 1887

As epidemics swept across the United States in the 19th century, the US government recognized the pressing need for a national lab dedicated to the study of infectious disease. 

The Literature

Hiding Under a Cap

Hiding Under a Cap

Editor's Choice in Immunology

The Axis of Aging

The Axis of Aging

Editor's choice in developmental biology

A Joint Endeavor

A Joint Endeavor

Editor's selection in physiology

Approaching Universality

Approaching Universality

Pitfalls and triumphs on the way to complete vaccine protection.

Speaking of Science

Speaking of Science

Speaking of Science

June 2011's selection of notable quotes

Notebook

One Bad Apple

One Bad Apple

A unique virus and the worm it infects turn up in an orchard outside of Paris.

Summit Science

Summit Science

Researchers seeking a link between vision problems and the dangerous physiological effects of hypoxia in mountain climbers are taking their work to new heights.

Cellular Salve

Cellular Salve

Ivan Martin talks about the promise of using cell-based therapies to regenerate joint cartilage.

Simultaneity

Simultaneity

Two research teams studying a rare genetic disorder discover independently that it's caused by genes that are crucial to DNA replication.

Bio Business

Take Two of These

Take Two of These

Take Two of These

Drugmakers are teaming up to test the disease-fighting power of combination therapies earlier in the development cycle than ever before.

Thought Experiment

First, Do No Harm…

First, Do No Harm…

Is DNA damage an inevitable consequence of epigenetic reprogramming?

Critic at Large

Hard and Harder

Hard and Harder

The path to eradicating malaria in Africa involves much more than just a vaccine.

Scientist to Watch

Dominique Bergmann: Probing Plant Pores

Dominique Bergmann: Probing Plant Pores

Assistant Professor, Department of Biology, Stanford University. Age: 41

Contributors

Contributors

Contributors

Meet some of the people featured in the June 2011 issue of The Scientist.

Capsule Reviews

Capsule Reviews

Capsule Reviews

In The Evolutionary World, Vermeij takes on the skeptics—both those with valid questions and those with irrational ones—and shows how the struggle for existence leads to variety and creativity.

Reading Frames

The Gravity of Life

The Gravity of Life

Whose well-being is threatened by our changing relationship with the myriad organisms that shaped the evolution of our species?

Lab Tools

Track Your Package

Track Your Package

Track Your Package

How to follow stem cells transplanted into living tissue.

Editorial

A Shot in the Arm

A Shot in the Arm

Decades of vaccine research have expanded our understanding of the immune system and are yielding novel disease-fighting tactics.