Cover Story

Vaccines
Robin A. Weiss and Peter Hale | Jun 1, 2011
Looking back, looking ahead

Features

The Last Vaccine Frontier
Brad Spellberg | Jun 1, 2011
Successful vaccines have been created to protect against pathogenic bacteria and viruses. Why aren’t there any for combating fungal infections?
Recognizing the Human Potential
Gene M. Shearer and Adriano Boasso | Jun 1, 2011
It may be time to reconsider an AIDS vaccine which is more human than viral, triggering the immune system in a way that no other vaccine does.
Shooting Down Addiction
Thomas Kosten | Jun 1, 2011
A new breed of vaccines aims to wean users off cocaine.

Foundations

One-Man NIH, 1887
One-Man NIH, 1887
As epidemics swept across the United States in the 19th century, the US government recognized the pressing need for a national lab dedicated to the study of infectious disease. 

The Literature

Hiding Under a Cap
Hiding Under a Cap
Editor's Choice in Immunology
A Joint Endeavor
A Joint Endeavor
Editor's selection in physiology
The Axis of Aging
The Axis of Aging
Editor's choice in developmental biology
Approaching Universality
Approaching Universality
Pitfalls and triumphs on the way to complete vaccine protection.

Speaking of Science

Speaking of Science
Speaking of Science
June 2011's selection of notable quotes

Notebook

One Bad Apple
One Bad Apple
A unique virus and the worm it infects turn up in an orchard outside of Paris.
Summit Science
Summit Science
Researchers seeking a link between vision problems and the dangerous physiological effects of hypoxia in mountain climbers are taking their work to new heights.
Cellular Salve
Cellular Salve
Ivan Martin talks about the promise of using cell-based therapies to regenerate joint cartilage.
Simultaneity
Simultaneity
Two research teams studying a rare genetic disorder discover independently that it's caused by genes that are crucial to DNA replication.

Bio Business

Take Two of These
Take Two of These
Take Two of These
Drugmakers are teaming up to test the disease-fighting power of combination therapies earlier in the development cycle than ever before.

Thought Experiment

First, Do No Harm…
First, Do No Harm…
Is DNA damage an inevitable consequence of epigenetic reprogramming?

Critic at Large

Hard and Harder
Hard and Harder
The path to eradicating malaria in Africa involves much more than just a vaccine.

Scientist to Watch

Dominique Bergmann: Probing Plant Pores
Dominique Bergmann: Probing Plant Pores
Assistant Professor, Department of Biology, Stanford University. Age: 41

Contributors

Contributors
Contributors
Meet some of the people featured in the June 2011 issue of The Scientist.

Capsule Reviews

Capsule Reviews
Capsule Reviews
In The Evolutionary World, Vermeij takes on the skeptics—both those with valid questions and those with irrational ones—and shows how the struggle for existence leads to variety and creativity.

Reading Frames

The Gravity of Life
The Gravity of Life
Whose well-being is threatened by our changing relationship with the myriad organisms that shaped the evolution of our species?

Lab Tools

Track Your Package
Track Your Package
Track Your Package
How to follow stem cells transplanted into living tissue.

Editorial

A Shot in the Arm
A Shot in the Arm
Decades of vaccine research have expanded our understanding of the immune system and are yielding novel disease-fighting tactics.