Hard and Harder

The path to eradicating malaria in Africa involves much more than just a vaccine.

Written byMichael K. Gusmano
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

Baby with malaria receiving quinine treatment in the port city of Kisumu in western Kenya. KAREN KASMAUSKI / CORBIS

Between 1955 and 1969, the Global Malaria Eradication Program, overseen by the World Health Organization (WHO), eliminated the disease from most developed countries. But worldwide eradication proved to be much more complex than its proponents had hoped. Strains of Anopheles and Aedes mosquitoes resistant to insecticides and of Plasmodium parasites resistant to drug treatment presented scientific challenges and increased the costs of eradication. Political instability in many parts of the developing world, and a lack of funding from donor countries, discouraged further eradication efforts for decades.

Today malaria remains a major public-health threat in sub-Saharan Africa, where 80 percent of the world’s known cases occur. In 2009, WHO reported 225 million cases of malaria and 781,000 deaths. While this was a decline from the 985,000 ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research