November 2004

Is science a young person's game?

or those pondering the cloning of their favorite feline should do a little research.

Your article made a very important point with respect to computer simulations of natural phenomena.

I couldn't disagree with you more.

One day early in November, all the doors of Stephen Minger's lab at King's College London were getting a fresh lick of pink paint in preparation for a royal visit.

On October 19, the Stanford Microarray Database recorded its 50,000th experiment since its creation in 1999.

The battlefield can be a laboratory for assessing response of the human body to stress.

Epilepsy often develops after the brain is damaged, and patients commonly must take anticonvulsant drugs for a lifetime despite unpleasant side effects.

Deciphering genetic relationships in cognitive function takes serious effort.

Like Sting's omnipresent voyeur, specialized mechanisms in the cells of higher organisms carefully monitor oxygen intake.

Tissue engineering has taken on a new meaning in recent years, bringing the stuff of science fiction to the operating table.

Today, gene therapy, genomics, and stem cell therapy are considered to be discrete fields of research.

Plants export wax from epidermal cells to their external surfaces through a lipid transporter similar to those present in mammalian cells, according to a study from the University of British Columbia.

Findings on Fugu gene splicing could help scientists develop pufferfish transgenes for mammalian cells, say researchers at Massachusetts Institute of Technology.

Courtesy of Mike SextonThese papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.L. Li et al., "A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death," Science, 305:1471–4, Sept. 3, 2004.This is the first study in which a true Smac mimetic was synthesized to antagonize the inhibitor-of-apoptosis (IAP) proteins. … Importantly, these compounds synergize with TNFα and

Most biological microscopes delve deep into the cell, imaging optical slices that can be put together into a three-dimensional rendering of what lies beneath the cell membrane.

In the mid-1950s, Princeton University researcher Marvin Minsky sought a way to increase signal-to-noise when imaging central nervous system samples.

Scientists at the Pacific Northwest National Laboratory in Richland, Wash., have used an established technique to observe real-time interactions between single protein molecules for the first time.

Microarrays are wonderful tools for seeing global patterns of gene expression under different conditions.

Researchers at York University in Toronto are refining a new bioanalytical technique capable of simultaneously analyzing hundreds or thousands of proteins in individual human cells.

Pathology labs worldwide face a shortage of trained histopathologists, says Dennis Chenoweth, corporate vice president of diagnostics at DakoCytomation of Carpinteria, Calif.

Close may be good enough for horseshoes and hand grenades, but analyzing proteins requires hard numbers.

An idea has been brewing quietly for years among doctors, healthcare policy wonks, medical journal editors, and others who make it their business to keep a close eye on the workings of the pharmaceutical industry.

As NexMed's director of human resources, Linda Burns often sends flowers to hospitalized employees.

Many chief executive officers of both profitable and not-yet-profitable biotechnology companies have multimillion-dollar pay packages, according to three recent surveys.

Matthew Meselson and Franklin Stahl's 1957 demonstration of DNA replication is considered "the most beautiful experiment in biology."