WIKIPEDIA, MIGUEL ANDRADE
A lot more oversight is needed to ensure omics-based technologies are effective and ready for clinical use, an Institute of Medicine (IOM) report concluded last week. Particularly when results from omics-based tests are used to devise therapies and medical interventions for patients, researchers and healthcare institutions should be sure that the tests have been proven scientifically valid.
The National Cancer Institute commissioned the report after omics-based tests developed by Duke University researchers were found to be based on faulty and fraudulent statistical models. The problematic tests were used in three clinical trials for determining the most effective chemotherapy treatment for lung and breast cancer patients. The scandal has since led to multiple paper retractions as well as lawsuits from patients involved in the trials.
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