Neural Connections Bolstered in Monkeys That Lift Weights

A study in two macaques reveals the importance of increasing connectivity between muscles and the reticulospinal tract that runs from the brain stem down the spinal cord.

Written byJef Akst
| 3 min read

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The paper
I.S. Glover, S.N. Baker, “Cortical, corticospinal, and reticulospinal contributions to strength training,” J Neurosci, 40:5820–32, 2020.

Of the two major neural highways that carry messages about movement down the spinal cord, one—the reticulospinal tract—is decidedly less fashionable, according to neuroscientist Stuart Baker of Newcastle University in the UK. In contrast to the corticospinal tract (CST), which evolved more recently and helps control complex, uniquely human movements such as playing the piano, the reticulospinal tract (RST) is associated with “boring” functions such as posture and walking, Baker says. But he suspects that the RST plays a bigger role in our movements than researchers currently appreciate.

To test for the RST’s possible contribution to strength training, Baker’s PhD student Isabel Glover, now a postdoc at University College London, taught two macaque monkeys to grasp and pull a handle attached to a pulley with their right paws. Feeding ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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