Directly activating a heat sensor also sensitive to capsaicin in chili peppers in the hypothalamus had the same effect as exercise.

Epinephrine’s activation of the signaling pathway Hippo is responsible for the in vitro tumor-fighting effects of serum from women who worked out.

Male rodents given access to a running wheel early in life show increased neural activity and improved memory as adults.

Researchers at the Society for Neuroscience discuss what we know—and don’t—about how physical activity affects the brain.

Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.

Running releases an enzyme that is associated with memory function in mice and humans.
 

At the American Association for Cancer Research annual meeting, researchers review the evidence that exercise has antitumor benefits.

Leptin, the satiety hormone produced by fat, affects neuronal signaling in the mouse brain; interference with this pathway can influence the rewarding effects of running in the animals.

Researchers who first identified irisin quantitate levels of the hormone in human blood and show it is released during exercise.